USPTO Patent Grant: Lipase for Metal Reduction in Distillers Corn Oil

ChangeBridge: Patent Grants - Biotech (C12N)

Published March 24th, 2026

Detected March 24th, 2026

Summary

The USPTO has granted a patent (US12584150B2) to POET Research, Inc. for a method using endogenous lipase to reduce metal content in distillers corn oil (DCO). This DCO is intended for use as a feedstock in renewable diesel production.

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What changed

The United States Patent and Trademark Office (USPTO) has issued patent US12584150B2 to POET Research, Inc. The patent covers compositions and methods for reducing metal ion content in distillers corn oil (DCO) by employing endogenous esterase, such as lipase, during biochemical production processes. This refined DCO is specifically noted as being useful for the production of renewable diesel.

This patent grant represents a new intellectual property development in the field of biofuel feedstock refinement. While not a regulatory mandate, it signifies a technological advancement that may influence industry practices in the production of renewable fuels. Companies involved in bio-chemical production, oil refining, and renewable diesel manufacturing should be aware of this patented technology, particularly if their processes involve distillers corn oil or similar co-products.

Source document (simplified)

← USPTO Patent Grants

Endogenous lipase for metal reduction in distillers corn oil

Grant US12584150B2 Kind: B2 Mar 24, 2026

Assignee

POET Research, Inc.

Inventors

Andrew J. Manning, Alex T. McCurdy, Steven T. Bly

Abstract

Provided herein are compositions, methods, systems associated with propagation and fermentation, and co-products of biochemical production processes, for example, a DCO co-product resulting from converting oil containing grains into bio chemicals via fermentation in the presence of endogenous esterase. The DCO resulting from the processes exhibits lower metal ion content relative to a DCO obtained in the absence of endogenous fermentation with an esterase such as a lipase. The DCO is useful as a feedstock for the production of renewable diesel.