Recombinant AAV Vectors for Treating Proteinopathies in CNS

The USPTO published patent application US20260091134A1 by Shanghai Vitalgen Biopharma Co., Ltd. covering recombinant adeno-associated viral (rAAV) vectors encoding Progranulin (PGRN) and/or Stathmin-2 (STMN2) for treating proteinopathies in the central nervous system. The application, filed November 26, 2025 (Application No. 19401460), includes codon-optimized coding sequences and viral particle compositions.

Rod-Derived Cone Viability Factor Fusion Protein

USPTO published patent application US20260091133A1 disclosing a fusion protein comprising rod-derived cone viability factor-S (RdCVF-S), a hydrophilic peptide, and a signal peptide. The invention covers encoding nucleic acids, viral vectors, and pharmaceutical compositions for potential treatment of ocular conditions. Inventors: Tianci LUO, Daniel LIPUT, Fong Qi LIANG. Application No. 19339969 filed September 25, 2025.

Apparatus for Extracorporeal Blood Treatment and Method for Determining Water Losses in Membrane Gas Exchanger

The USPTO published patent application US20260091165A1 by Dominique Pouchoulin for an apparatus used in extracorporeal blood treatment. The invention includes a method for determining water losses in a membrane gas exchanger by measuring sweep gas flow rate and water saturation content at the gas outlet. This technology applies to dialysis and similar blood treatment systems.

Removable Inlet Manifold for Medical Waste Collection System

The USPTO published patent application US20260091166A1 on April 2, 2026, disclosing a removable inlet manifold for medical and surgical waste collection systems. The manifold features a tube that extends through an inlet port into a manifold cage and engages a complementary valve in the receiver to regulate fluid flow. Inventors include Andrew Mills, David Noskowicz, Brian Barkeley, Zachary Zott, and Stuart Mintz. Application No. 19412854 was filed December 9, 2025.

Electric Nasal Suction Device with Secondary Air Gap Chamber

The USPTO published patent application US20260091167A1 for an electric nasal suction device featuring a secondary air gap chamber positioned between a collection chamber and an air pump. The application was filed on January 16, 2025, by inventors Sophia Fornaro, John Fritz, Bailey Denton, and Chelsea Hirschhorn. The device falls under CPC classification A61M 1/67 and A61M 2210/0618, indicating medical suction apparatus technology.

Infusion pump syringes with reduced flexing, improved sealing

The USPTO published patent application US20260091168A1 for syringes designed for infusion pumps with reduced flexing and improved sealing. Invented by James Jacobson et al., the application (filed September 18, 2023) covers syringe barrel, plunger rod, and seal designs suited for infusion pumps with frequent start/stop operations at low flow rates. CPC classifications include A61M 5/1452 and related subclasses.

Pump Device and Associated Method for Medication Delivery

The USPTO published patent application US20260091169A1 for a pump device with chamber, plunger, retainer, rods, and button mechanism designed for controlled medication delivery through an outlet. Assignee is Evanesce Medical, Inc. with four inventors. The application was filed on September 30, 2025.

Safety control system of a drug injection system

The USPTO published patent application US20260091170A1 for a safety control system of a drug injection system, filed by inventors Chin-Min YEH and Chih-Wei WANG. The system includes a contact end cap and confirming switch to activate a control unit for injection preparation, improving safety performance. Application No. 18899532 was filed on September 27, 2024.

Dual-Plunger Syringe Assembly for Administering Multiple Fluids

The USPTO published patent application US20260091171A1 for a dual-plunger syringe assembly that enables administration of multiple fluids through a single device. Inventor Abraham C. Ng filed the application (No. 18902936) on October 1, 2024. The design embeds a second plunger within a first plunger, allowing sequential or simultaneous delivery of two distinct fluids.

Wearable Thermal Sensors for Subdermal Fluid Monitoring

The USPTO published patent application US20260091172A1 by Rhaeos Inc. disclosing a wearable thermal sensor system for monitoring subdermal fluid levels. The system includes at least six temperature sensors, three thermal actuators, a flexible substrate, and a microprocessor configured to trigger alerts based on calculated alert conditions from temperature readings.