Amplifier Interface for Multi-Electrode Catheter

USPTO published patent application US20260090755A1 for an amplifier interface system used in multi-electrode cardiac catheter procedures. The invention by Brian Pederson and Greg Olson describes a switching matrix that selectively couples catheter electrodes to amplifier channels, allowing flexible electrode selection despite a fixed number of amplifier channels. The system classifies under CPC categories A61B 5/304 and A61B 18/10.

Atrial Fibrillation Trigger Detection Using Electrode Signal Correlation

USPTO published Biosense Webster (Israel) Ltd.'s patent application (US20260090756A1) for a method of detecting atrial fibrillation triggers using composite correlation scores based on signals from multiple electrodes. The invention relates to electro-anatomical mapping systems that identify suspected AF trigger locations in the heart by analyzing electrode signal correlations. Application No. 18903377 was filed October 1, 2024.

Wearable ECG Systems with Automatic Vagus Nerve Stimulation

The USPTO published patent application US20260090757A1 by inventor David C. Shaw for wearable electrocardiogram (ECG) monitoring systems with automatic anti-arrhythmia capabilities. The application covers ECG systems that record from ears, fingers, or toes and include transcutaneous auricular vagus nerve stimulation (taVNS) to automatically detect and treat serious cardiac arrhythmias. Filing date was September 18, 2025.

Cognitive-Impairment Diagnostics For Schizophrenia

USPTO published patent application US20260090758A1 by Bristol-Myers Squibb Company for a method of diagnosing cognitive impairment in schizophrenia patients using electrical brain activity measurements. The invention processes neural activity data from electrodes attached to a patient's head along with stimulation data to determine modulation depth for cognitive assessment.

Skin Condition Examination Using Electric Field Imaging

USPTO published patent application US20260090760A1 by inventor Hrand Mami MAMIGONIANS on April 2, 2026. The application discloses a method for examining visible skin conditions by combining camera-based image capture with electric field imaging to assess depth of skin penetration through correlation of surface area and volume measurements.

Wearable Device for Measuring Skeletal Muscle Hardness

USPTO published patent application US20260090761A1 by J.Schmalz GmbH for a wearable measuring device designed to monitor skeletal muscle hardness using multiple force sensors with varying spring constants. The device includes a holding apparatus for attachment to body parts and can detect tensioning forces from different muscle sections.

Amino acid-modified lipids enable RNA delivery via lipid nanoparticles

USPTO published patent application US20260091126A1 for amino acid-modified lipids designed for RNA delivery via lipid nanoparticles (LNPs). The application, filed September 19, 2023, by inventors Kun Cheng and Pratikkumar Vinodchandra Patel, covers siRNA, mRNA, miRNA, shRNA, and oligonucleotide delivery formulations. The technology targets oncogene silencing applications.

Cell-Penetrating Peptides for Muscular Dystrophy Treatment

USPTO published patent application US20260091120A1 by Matthew Wood et al. covering cell-penetrating peptides with dual hydrophobic domains for treating genetic disorders, specifically Duchenne muscular dystrophy. The application (filed October 21, 2025) discloses peptide compositions and conjugates with therapeutic molecules. This is a publication of a pending application and does not yet grant enforceable patent rights.

ASXL1 Disruption in T Cells for Immunotherapy Enhancement

The USPTO published patent application US20260091115A1 filed by St. Jude Children's Research Hospital, Inc., covering modified immune effector cells with disrupted ASXL1 genes for enhanced immunotherapy function. The application includes claims for the modified T cells, methods of generating them, and methods for using them in adoptive cell therapy treatments for diseases.

Biallelic Knockout of CTLA4

The USPTO published patent application US20260091113A1 by inventor Rafi Emmanuel covering compositions and methods for biallelic knockout of CTLA4 using RNA guide sequences. The application includes 4,891 sequence variants (SEQ ID NOs: 1-4891) with potential therapeutic applications. Filed September 18, 2023; published April 2, 2026.