Cognitive-Impairment Diagnostics For Schizophrenia

ChangeBridge: Patent Apps - Diagnosis & Surgery (A61B)

Published April 2nd, 2026

Detected April 2nd, 2026

Summary

USPTO published patent application US20260090758A1 by Bristol-Myers Squibb Company for a method of diagnosing cognitive impairment in schizophrenia patients using electrical brain activity measurements. The invention processes neural activity data from electrodes attached to a patient's head along with stimulation data to determine modulation depth for cognitive assessment.

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What changed

The patent application describes a diagnostic method that receives electrical activity data from electrodes on a patient's head representing neural activity in corresponding brain areas, along with stimulation data representing stimulation times applied to the patient. The method processes this data to determine a modulation depth and assess cognitive impairment due to schizophrenia. The CPC classifications indicate this falls under A61B (measuring/diagnosing), specifically EEG/electrical brain activity monitoring (A61B 5/291, A61B 5/388) and cognitive assessment technologies (A61B 5/4088).\n\nAs this is a patent application rather than enacted regulation, there are no immediate compliance obligations for healthcare providers or medical device manufacturers. However, companies developing similar neurodiagnostic or cognitive assessment technologies should monitor this application's prosecution to understand potential scope of any future granted claims that might affect their freedom to operate. The inventors are Ryan Allen Shewcraft, Mariann Micsinai Balan, and John Carter Schwarz.

Source document (simplified)

← USPTO Patent Applications

Cognitive-Impairment Diagnostics For Schizophrenia

Application US20260090758A1 Kind: A1 Apr 02, 2026

Assignee

Bristol-Myers Squibb Company

Inventors

Ryan Allen Shewcraft, Mariann Micsinai Balan, John Carter Schwarz

Abstract

A method includes, for each corresponding electrode of one or more electrodes attached to a head of a patient, receiving corresponding electrical activity data representing neural activity within a corresponding area of a brain of the patient based on corresponding electrical activity measured by the corresponding electrode. The method also includes receiving stimulation data representing a plurality of stimulation times each corresponding to a stimulation applied to the patient while the one or more electrodes are attached to the head of the patient, and processing the corresponding electrical activity data and the stimulation data to determine a modulation depth for the patient. The method also includes assessing, based on the modulation depth, cognitive impairment of the patient due to a diagnosis of schizophrenia.