USPTO Patent Grant: Microbial Polypeptides for Glycogen Storage Diseases

The USPTO has granted patent US12582724B2 to Duke University for compositions comprising microbial polypeptides designed to treat glycogen storage diseases. The patent covers isolated nucleic acid molecules, vectors, and methods utilizing these components for therapeutic purposes.

USPTO Patent Grant US12582723B2 for FKRP Protein Polynucleotides

The USPTO has granted patent US12582723B2 to Genethon for synthetic polynucleotides encoding a human FKRP protein. These polynucleotides are designed to avoid frameshift mutations and are useful for treating pathologies linked to FKRP deficiency or defects in alpha-dystroglycan glycosylation, such as LGMD2I.

USPTO Patent US12582141B2: Phytase Activity Polypeptides

The USPTO has granted patent US12582141B2 to AB Enzymes Finland Oy for novel polypeptides with improved phytase activity. The patent covers compositions, recombinant host cells, and their use in feed applications.

USPTO Patent Granted for ST Gal(+) Bacteria in Fermented Milk

The USPTO has granted a patent (US12582133B2) to Chr. Hansen A/S for a method using ST Gal(+) bacteria to produce fermented milk products with a high stable pH. The patent covers specific bacterial strains and their application in food production.

USPTO Patent Grant: IL-15 Humanized Mouse Model

The USPTO has granted patent US12582106B2 for an IL-15 humanized mouse model and its use, assigned to GEMPHARMATECH CO., LTD. The patent details a specific genetic modification of the mouse, combining human and mouse gene segments, and outlines its preparation and application, particularly in cancer research.

Neighborhood Reinvestment Corporation Sunshine Act Meeting Notice

The Neighborhood Reinvestment Corporation has issued a notice for a Special Board of Directors meeting to be held on March 30, 2026. The meeting will include both open and closed sessions, with the closed session pertaining to the FY26 Final Budget.

USPTO PTAB Adds New IPR, CBM, and PGR Decisions

The USPTO's Patent Trial and Appeal Board (PTAB) has added new decisions for Inter Partes Review (IPR), Covered Business Method (CBM), and Post-Grant Review (PGR) proceedings. These include final written decisions for cases involving Bio-Rad Laboratories, Inc. v California Institute of Technology and Google LLC v Ericsson AB, as well as 'Settled After Institution' decisions.

Missouri Agencies Alert Public to Rising Nitazene Threat

Missouri state agencies have issued a joint warning about the increasing presence of nitazenes, a potent synthetic opioid, detected in wastewater and illicit substances across the state. The alert urges public vigilance, prevention measures, and expanded access to naloxone, a life-saving overdose reversal medication.

Commonwealth Edison Company Expedited Petition for Rate Increase Waiver

Commonwealth Edison Company has filed an expedited petition with the State PUC for a waiver of certain rate increase provisions. The filing seeks to bypass standard information requirements for public utilities seeking rate hikes. The case is currently in its initial administrative phase with action pending.

Solarize LLC Installer Certification Application

The Illinois State PUC received an application from Solarize LLC for certification as an installer of distributed generation facilities. This filing pertains to case number P2026-0272 and is part of the ongoing process for installer certification under the Public Utilities Act.