SCYNEXIS patent for triterpenoid antifungals treating Pneumocystis pneumonia

The USPTO issued patent US12594266B2 to SCYNEXIS, INC. on April 7, 2026, covering eufumafungin derivative triterpenoid antifungal compounds and their use in treating or preventing Pneumocystis pneumonia (PCP). The patent includes 16 claims encompassing the compound structures, pharmaceutical compositions, and methods of treatment.

Methods for treating inflammatory skin conditions (minocycline)

USPTO granted Journey Medical Corporation Patent US12594252B2 covering methods of treating inflammatory skin conditions using reduced-dose minocycline compositions. The patent, with 39 claims, names six inventors including Swati Kulkarni and Rajeev Singh Raghuvanshi. The invention relates to administering a pharmaceutical composition comprising a reduced dose of minocycline to achieve effective plasma or interstitial fluid concentrations for treating inflammatory skin conditions.

Patent US12594280B2: Antiviral Compositions for Influenza Treatment

USPTO granted Patent US12594280B2 to Universite Claude Bernard Lyon 1 covering antiviral pharmaceutical compositions containing Etilefrine and Diltiazem for preventing and treating influenza virus infections. The patent includes 10 claims and covers the use of these compounds in veterinary and pharmaceutical compositions.

Mitochondria-targeted atovagone compounds and methods for antitumor, antimicrobial, and antimalarial treatment

USPTO granted Patent US12594283B2 to The Medical College of Wisconsin, Inc. covering mitochondria-targeted Atovaquone compounds (Mito-ATO) and methods of using such compounds for antitumor, antimicrobial, and antimalarial treatment. The patent contains 22 claims and was filed on October 26, 2020.

Cambridge Cognition Patent - Combination Therapy for Schizophrenia

The USPTO granted Patent US12594270B2 to Cambridge Cognition Limited on April 7, 2026. The patent covers a combined therapy comprising alpha-7 nicotinic acetylcholine receptor activators with 5-HT3 receptor inhibitory activity combined with 5-HT3 receptor activators for treating schizophrenic disorders. The patent contains 21 claims and names Kiri Granger and Jennifer Barnett as inventors.

BASF SE Amylase Variants for Laundry, Cleaning, and Industrial Enzymes

The USPTO granted patent US12595471B2 to BASF SE for genetically engineered amylase enzyme variants with enhanced stability and activity. The patent covers compositions and methods for using these enzymes in laundry detergents, dish washing detergents, cleaning products, baking, animal feed, pulp and paper processing, starch processing, brewing, and ethanol production. The patent includes 18 claims and names Stefan Jenewein, Zachary David Miles, and Priya Anand as inventors.

DNA Data Storage on Two-Dimensional Support Material Patent Grant

The USPTO granted Patent US12595474B2 to Microsoft Technology Licensing, LLC for a DNA-based data storage medium utilizing two-dimensional support structures. The invention comprises synthetic DNA molecules encoding digital information placed on metal foil, glass, or plastic supports, protected by silica or metal encapsulation layers. The patent enables geometric addressability for selective access to specific digital information stored in DNA format.

Endoscope System and Coordinate System Correction Method

USPTO granted Patent US12593962B2 to Olympus Corporation covering an endoscope system with automated coordinate correction. The patent describes methods for detecting endoscope movement direction, estimating moving body areas in captured images, and calculating deviations between endoscope and moving device coordinate systems to enable automatic correction.

Patent B2, cardioembolic stroke diagnosis via chest X-rays

The USPTO granted Patent US12594046B2 to Seoul National University Hospital on April 7, 2026. The patent covers a method and apparatus for assisting diagnosis of cardioembolic stroke using chest radiographic images analyzed by a neural network model. Inventors are Han-Gil Jeong and Tackeun Kim.

Posterolateral Instrumentation Treatment System and Methods - Spinal Surgery Patent

The USPTO granted patent US12594098B2 to the Board of Trustees of the University of Illinois for a posterolateral instrumentation treatment system and methods for spinal surgery. The patent covers a spinal fixation system including a cannulated bone rod designed for controlled fluid delivery to bone and surrounding tissue during surgical procedures. Key claims include a bone screw with longitudinal access, a bone rod positioned laterally to the longitudinal axis, and methods for delivering fluids or using the fixation system as a drainage point for posterolateral fusion sites. The patent has 19 claims with CPC classifications A61B 17/7017 and A61B 17/7002.