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ESPB vs ICNB Postoperative Pain VATS Randomized Trial

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Summary

NIH's ClinicalTrials.gov has registered study NCT07535697, a prospective randomized trial comparing ultrasound-guided erector spinae plane block (ESPB) to thoracoscopically-guided intercostal nerve block (ICNB) for postoperative pain management in adults undergoing video-assisted thoracoscopic surgery (VATS). The study will evaluate analgesic consumption over 24 hours, pain levels at predefined time points, and procedure duration to determine whether ESPB provides comparable analgesia to ICNB.

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What changed

NIH's ClinicalTrials.gov has registered a new randomized comparative study (NCT07535697) evaluating two regional anesthesia techniques for postoperative pain control after video-assisted thoracoscopic surgery. The study will enroll adults undergoing elective VATS lung resection and randomly assign participants to receive either ultrasound-guided erector spinae plane block (ESPB) performed by anesthesiologists or thoracoscopically-guided intercostal nerve block (ICNB) performed by surgeons.

Healthcare providers and clinical investigators involved in thoracic surgery pain management may find this study relevant for evidence-based practice. The findings could inform clinical decisions regarding optimal regional anesthesia techniques for VATS procedures. The study's completion and publication of results may influence standard care practices for perioperative pain management in thoracic surgery settings.

Archived snapshot

Apr 18, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Ultrasound-Guided Erector Spinae Plane Block Versus Thoracoscopically-Guided Intercostal Nerve Block in Video-Assisted Thoracoscopic Surgery: A Prospective Randomized Study Evaluating Postoperative Analgesic Consumption, Pain Perception and Procedure Duration

N/A NCT07535697 Kind: NA Apr 17, 2026

Abstract

Effective postoperative pain management is essential after thoracic surgery. Insufficient pain control may impair breathing and coughing, increasing the risk of pulmonary complications such as collapsed lungs (atelectasis) or pneumonia.

Although minimally invasive lung surgery (video-assisted thoracoscopic surgery, VATS) is less painful than open surgery, people can still have significant pain after the operation.

The goal of this randomized comparative study is to compare two commonly used regional anesthesia techniques for pain control after VATS in adults.

Researchers will compare an ultrasound-guided erector spinae plane block (ESPB), performed by anesthesiologists, to a thoracoscopically-guided intercostal nerve block (ICNB), performed by surgeons.

Participants will:

  • Undergo elective VATS lung resection surgery
  • Receive either ESPB or ICNB, according to random assignment
  • Have the received amount of analgesics recorded during the first 24 hours
  • Have their pain levels assessed at predefined time points after surgery

The main questions this study aims to answer are:

  • Does ESPB result in similar analgesic consumption in the first 24 hours after surgery?
  • Does ESPB provide similar postoperative pain relief compared to ICNB?
  • Is the time needed to perform ESPB similar to ICNB?

Conditions: Regional Anesthesia, Video-assisted Thoracoscopic Surgery (VATS), Erector Spinae Plane Block, Intercostal Nerve Block

Interventions: Anesthesiological, Ultrasound-Guided "Erector Spine Plane Block" (ESPB), Surgical, Thoracoscopically-Guided "Intercostal Nerve Block" (ICNB)

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Last updated

Classification

Agency
NIH
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07535697
Docket
NCT07535697

Who this affects

Applies to
Clinical investigators Healthcare providers
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Postoperative pain management research Regional anesthesia evaluation
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Compliance frameworks
GxP
Topics
Pharmaceuticals

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