ESPB vs ICNB Postoperative Pain VATS Randomized Trial
Summary
NIH's ClinicalTrials.gov has registered study NCT07535697, a prospective randomized trial comparing ultrasound-guided erector spinae plane block (ESPB) to thoracoscopically-guided intercostal nerve block (ICNB) for postoperative pain management in adults undergoing video-assisted thoracoscopic surgery (VATS). The study will evaluate analgesic consumption over 24 hours, pain levels at predefined time points, and procedure duration to determine whether ESPB provides comparable analgesia to ICNB.
What changed
NIH's ClinicalTrials.gov has registered a new randomized comparative study (NCT07535697) evaluating two regional anesthesia techniques for postoperative pain control after video-assisted thoracoscopic surgery. The study will enroll adults undergoing elective VATS lung resection and randomly assign participants to receive either ultrasound-guided erector spinae plane block (ESPB) performed by anesthesiologists or thoracoscopically-guided intercostal nerve block (ICNB) performed by surgeons.
Healthcare providers and clinical investigators involved in thoracic surgery pain management may find this study relevant for evidence-based practice. The findings could inform clinical decisions regarding optimal regional anesthesia techniques for VATS procedures. The study's completion and publication of results may influence standard care practices for perioperative pain management in thoracic surgery settings.
Archived snapshot
Apr 18, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Ultrasound-Guided Erector Spinae Plane Block Versus Thoracoscopically-Guided Intercostal Nerve Block in Video-Assisted Thoracoscopic Surgery: A Prospective Randomized Study Evaluating Postoperative Analgesic Consumption, Pain Perception and Procedure Duration
N/A NCT07535697 Kind: NA Apr 17, 2026
Abstract
Effective postoperative pain management is essential after thoracic surgery. Insufficient pain control may impair breathing and coughing, increasing the risk of pulmonary complications such as collapsed lungs (atelectasis) or pneumonia.
Although minimally invasive lung surgery (video-assisted thoracoscopic surgery, VATS) is less painful than open surgery, people can still have significant pain after the operation.
The goal of this randomized comparative study is to compare two commonly used regional anesthesia techniques for pain control after VATS in adults.
Researchers will compare an ultrasound-guided erector spinae plane block (ESPB), performed by anesthesiologists, to a thoracoscopically-guided intercostal nerve block (ICNB), performed by surgeons.
Participants will:
- Undergo elective VATS lung resection surgery
- Receive either ESPB or ICNB, according to random assignment
- Have the received amount of analgesics recorded during the first 24 hours
- Have their pain levels assessed at predefined time points after surgery
The main questions this study aims to answer are:
- Does ESPB result in similar analgesic consumption in the first 24 hours after surgery?
- Does ESPB provide similar postoperative pain relief compared to ICNB?
- Is the time needed to perform ESPB similar to ICNB?
Conditions: Regional Anesthesia, Video-assisted Thoracoscopic Surgery (VATS), Erector Spinae Plane Block, Intercostal Nerve Block
Interventions: Anesthesiological, Ultrasound-Guided "Erector Spine Plane Block" (ESPB), Surgical, Thoracoscopically-Guided "Intercostal Nerve Block" (ICNB)
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