Changeflow GovPing Pharma & Drug Safety USPTO Patent Application: TYK2 Inhibitor Dosage...
Routine Notice Added Final

USPTO Patent Application: TYK2 Inhibitor Dosage Forms

Favicon for changeflow.com ChangeBridge: Patent Apps - Pharma (A61K)
Published December 2nd, 2025
Detected March 26th, 2026
Email

Summary

The USPTO has published a patent application (US20260083733A1) for novel dosage forms of a TYK2 inhibitor, BMS-986165, intended for treating autoimmune diseases. The application details stable and bioavailable formulations, including spray-dried dispersions in a solid polymer matrix.

What changed

This document is a USPTO patent application (US20260083733A1) for new dosage forms of a TYK2 inhibitor, identified as BMS-986165. The application, filed on December 2, 2025, describes formulations designed to be stable and bioavailable, specifically mentioning spray-dried dispersions within a solid polymer matrix. These formulations are intended for the treatment of autoimmune and auto-inflammatory diseases, including inflammatory bowel disease (IBD) and psoriasis.

As this is a patent application, it does not impose direct compliance obligations on regulated entities. However, it signifies potential future intellectual property and market exclusivity for specific drug formulations. Pharmaceutical and drug manufacturers involved in the development of TYK2 inhibitors or treatments for autoimmune diseases should monitor this application and related patents for competitive intelligence and potential licensing opportunities.

Source document (simplified)

← USPTO Patent Applications

DOSAGE FORMS FOR TYK2 INHIBITORS

Application US20260083733A1 Kind: A1 Mar 26, 2026

Inventors

Sherif Ibrahim Farag Badawy, Jonathan R. Brown, Candice Y. Choi, Christoph Gesenberg, Vivienne Gray, John Wynne Jones, Umesh Kestur, Balvinder S. Vig, Xiaotian S. Yin, Christopher A. Zordan, Corey Bloom, lan Yates

Abstract

Stable and bioavailable formulations and dosage forms comprising a dispersion (e.g., spray-dried dispersion) of solid amorphous 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide (Formula (I); BMS-986165) in a solid polymer matrix are provided for the treatment of auto-immune and auto-inflammatory diseases such as an inflammatory bowel disease (IBD) and psoriasis:

CPC Classifications

A61K 31/501 A61K 9/0053 A61K 9/2009 A61K 9/2013 A61K 9/2018 A61K 9/2054 A61K 9/284 A61K 45/06

Filing Date

2025-12-02

Application No.

19406921

View original document →

Named provisions

DOSAGE FORMS FOR TYK2 INHIBITORS

Classification

Agency
USPTO
Published
December 2nd, 2025
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260083733A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Formulation
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Drug Development Intellectual Property

Get Pharma & Drug Safety alerts

Weekly digest. AI-summarized, no noise.

Free. Unsubscribe anytime.

Get alerts for this source

We'll email you when ChangeBridge: Patent Apps - Pharma (A61K) publishes new changes.

Optional. Personalizes your daily digest.

Free. Unsubscribe anytime.