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DOSAGE FORMS FOR TYK2 INHIBITORS

Application US20260083733A1 Kind: A1 Mar 26, 2026

Inventors

Sherif Ibrahim Farag Badawy, Jonathan R. Brown, Candice Y. Choi, Christoph Gesenberg, Vivienne Gray, John Wynne Jones, Umesh Kestur, Balvinder S. Vig, Xiaotian S. Yin, Christopher A. Zordan, Corey Bloom, lan Yates

Abstract

Stable and bioavailable formulations and dosage forms comprising a dispersion (e.g., spray-dried dispersion) of solid amorphous 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide (Formula (I); BMS-986165) in a solid polymer matrix are provided for the treatment of auto-immune and auto-inflammatory diseases such as an inflammatory bowel disease (IBD) and psoriasis:

CPC Classifications

A61K 31/501 A61K 9/0053 A61K 9/2009 A61K 9/2013 A61K 9/2018 A61K 9/2054 A61K 9/284 A61K 45/06

Filing Date

2025-12-02

Application No.

19406921