USPTO Patent Application for Acute Migraine Treatment with Ubrogepant
Summary
The USPTO has published a new patent application (US20260083710A1) detailing methods for the acute treatment of migraine using the drug ubrogepant. The application includes specific claims related to treatment in patients with hepatic or renal impairment and those concurrently taking certain CYP3A4 modulators or BCRP/P-gp inhibitors.
What changed
The United States Patent and Trademark Office (USPTO) has published a patent application, US20260083710A1, concerning methods for the acute treatment of migraine. The application specifically covers the administration of ubrogepant, with particular emphasis on its use in patients experiencing hepatic or renal impairment, or those concurrently taking specific CYP3A4 modulators or BCRP and/or P-gp only inhibitors.
This publication represents a new patent application filing and does not impose immediate regulatory obligations on pharmaceutical companies. However, it signifies potential future intellectual property protection for ubrogepant-based migraine treatments, which may impact market exclusivity and competitive strategies for companies operating in the migraine therapeutic space. Companies developing or marketing similar treatments should monitor the progress of this patent application and consider its implications for their own product pipelines and intellectual property portfolios.
Source document (simplified)
TREATMENT OF MIGRAINE
Application US20260083710A1 Kind: A1 Mar 26, 2026
Inventors
Joel M. Trugman, Ramesh Boinpally, Abhijeet Jakate, Michelle Finnegan, Mary Ann Johnson, Leonardo R. Allain, W. Mark Eickhoff, Craig B. Ikeda, Chad D. Brown, Francis J. Flanagan, JR., Rebecca Nofsinger, Melanie J. Marota, Lisa Lupton, Paresh B. Patel, Hanmi Xi, Wei Xu
Abstract
The present disclosure provides methods for the acute treatment of migraine with or without aura, comprising the administration of ubrogepant. In particular, the present disclosure provides methods for the acute treatment of migraine in patients having hepatic impairment; in patients with renal impairment; and in patients concurrently taking CYP3A4 modulators or BCRP and/or P-gp only inhibitors.
CPC Classifications
A61K 31/4375 A61K 31/4545 A61P 25/06
Filing Date
2025-10-07
Application No.
19351985
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