Patent Application: Compositions and Methods for Reducing RNA Levels

ChangeBridge: Patent Apps - Biotech (C12N)

Published June 20th, 2023

Detected March 27th, 2026

Summary

The USPTO has published a new patent application (US20260085311A1) detailing compositions and methods for reducing RNA levels and treating diseases caused by toxic gain-of-function proteins. The application was filed on June 20, 2023.

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What changed

This document is a publication of a patent application filed with the USPTO, specifically application number US20260085311A1. The application, titled "Compositions and Methods for Reducing RNA Levels," describes methods for reducing RNA transcript levels and treating diseases resulting from toxic gain-of-function proteins. It was filed on June 20, 2023, by inventors Liana Lareau, Fyodor Urnov, and Ma. Carmelle Catamura.

As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on regulated entities. However, it represents potential future intellectual property in the biotechnology and pharmaceutical sectors. Companies involved in RNA-based therapeutics or disease treatment should be aware of this filing as it may impact future research, development, and patent landscapes.

Source document (simplified)

← USPTO Patent Applications

COMPOSITIONS AND METHODS FOR REDUCING RNA LEVELS

Application US20260085311A1 Kind: A1 Mar 26, 2026

Inventors

Liana Lareau, Fyodor Urnov, Ma. Carmelle Catamura

Abstract

The present disclosure provides methods for reducing the level of an RNA transcript from a target nucleic acid. The present disclosure provides methods of treating a disease that results from or is caused by a toxic gain-of-function protein. The present disclosure provides systems and compositions for carrying out a method of the present disclosure.