Patent Application: Compositions for Treating CHD2 Haploinsufficiency
Summary
The USPTO has published a patent application (US20260085319A1) for compositions and methods to treat CHD2 haploinsufficiency. The application details a method of increasing Chromodomain Helicase DNA Binding Protein 2 (CHD2) in neuronal cells using a nucleic acid agent.
What changed
This document is a published patent application from the USPTO, specifically application US20260085319A1, filed on August 26, 2025. It describes compositions and methods for treating CHD2 haploinsufficiency by increasing the amount of CHD2 protein in neuronal cells using a nucleic acid agent directed at the last exon of human Chaserr.
As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on entities. However, it signals potential future intellectual property and market exclusivity for novel treatments in this area. Companies involved in biotechnology, pharmaceuticals, and neurological treatments should monitor the progress of this application and related patents, as they may impact research and development strategies and market entry for therapies targeting CHD2 haploinsufficiency.
Source document (simplified)
COMPOSITIONS FOR USE IN THE TREATMENT OF CHD2 HAPLOINSUFFICIENCY
Application US20260085319A1 Kind: A1 Mar 26, 2026
Inventors
Igor ULITSKY, Caroline Jane ROSS
Abstract
A method of increasing an amount of Chromodomain Helicase DNA Binding Protein 2 (CHD2) in a neuronal cell is provided. The method comprising introducing into the cell a nucleic acid agent directed at the last exon of human Chaserr, thereby increasing the amount of CHD2 in the neuronal cell.
CPC Classifications
C12N 15/1137 A61P 25/00 G16B 30/10 C12N 2310/11 C12N 2310/321
Filing Date
2025-08-26
Application No.
19310181
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