Changeflow GovPing Pharma & Drug Safety Method for Treating Alzheimer's Disease
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Method for Treating Alzheimer's Disease

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Published April 2nd, 2026
Detected April 2nd, 2026
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Summary

The USPTO published patent application US20260091109A1 disclosing a method for treating Alzheimer's disease using sequential administration of anti-amyloid beta monoclonal antibodies in increasing doses to reduce ARIA risk. The application, filed June 16, 2025, names James L. Ferrero, Leslie Lugene Williams, and Jeffrey Joseph Sevigny as inventors. This publication provides public notice of a pending patent application but creates no compliance obligations for third parties.

What changed

The USPTO published patent application US20260091109A1 disclosing a method for treating Alzheimer's disease by sequentially administering multiple doses of a recombinant, fully human, anti-amyloid beta monoclonal antibody to a human patient. Preferred embodiments involve administering the antibody in increasing amounts over time to reduce susceptibility to amyloid related imaging abnormalities (ARIA). The application was filed June 16, 2025, and names James L. Ferrero, Leslie Lugene Williams, and Jeffrey Joseph Sevigny as inventors.

This is a patent application publication only. It provides public notice of a pending application but creates no compliance obligations for third parties. No action is required by pharmaceutical or biotechnology companies. Parties interested in the patent landscape for Alzheimer's treatments may review the application through USPTO records.

Source document (simplified)

← USPTO Patent Applications

Method for Treating Alzheimer's Disease

Application US20260091109A1 Kind: A1 Apr 02, 2026

Inventors

James L. Ferrero, Leslie Lugene Williams, Jeffrey Joseph Sevigny

Abstract

A method for treatment of a human patient for Alzheimer's disease (AD) comprises sequentially administering multiple doses of a recombinant, fully human, anti-amyloid beta monoclonal antibody to the patient. In preferred embodiments, the antibody is administered in increasing amounts over a period of time. In preferred embodiments, the susceptibility of the patient to amyloid related imaging abnormalities (ARIA) is thereby reduced.

CPC Classifications

A61K 39/3955 C07K 16/18 C07K 16/28 A61K 2039/505 A61K 2039/545

Filing Date

2025-06-16

Application No.

19239695

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Named provisions

Method for Treating Alzheimer's Disease Inventors Abstract CPC Classifications

Classification

Agency
USPTO
Published
April 2nd, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260091109A1

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Patent Applications Biopharmaceutical Research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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