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Adeno-Associated Virus Producer Cell Lines Patent Application

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Published April 2nd, 2026
Detected April 2nd, 2026
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Summary

The USPTO published patent application US20260092284A1 for Adeno-Associated Virus (AAV) producer cell lines and methods of producing AAVs. The application, filed August 15, 2025, covers nucleic acids encoding helper genes and AAV genes under inducible promoter control, as well as mammalian cell lines for AAV production. Inventors include Bingnan Gu, Gang Li, and Caitlin Tripp.

What changed

The USPTO published application US20260092284A1 covering mammalian cell lines engineered to produce adeno-associated viruses (AAVs) and methods for their use. The disclosure relates to nucleic acids encoding helper genes and AAV genes under inducible promoters, enabling controlled AAV production. CPC classifications indicate applications in gene therapy vector manufacturing (C12N 15/635, C07K 14/005).

This is a routine patent application publication rather than a regulatory action. Companies developing gene therapy products or AAV-based vectors may wish to review the claims to assess potential freedom-to-operate implications. No compliance deadlines or regulatory requirements are associated with this patent application publication.

Source document (simplified)

← USPTO Patent Applications

ADENO-ASSOCIATED VIRUS (AAV) PRODUCER CELL LINES

Application US20260092284A1 Kind: A1 Apr 02, 2026

Inventors

Bingnan GU, Gang LI, Caitlin TRIPP

Abstract

The present disclosure relates to nucleic acids encoding helper genes and adeno-associated virus (AAV) genes, under the control of inducible promoters. The disclosure also relates to a mammalian cell line for producing AAV as well as methods of using the mammalian cells for producing AAVs.

CPC Classifications

C12N 15/635 C07K 14/005 C12N 15/85 C12N 2710/16222 C12N 2760/14122 C12N 2830/003

Filing Date

2025-08-15

Application No.

19300921

View original document →

Named provisions

Abstract Inducible Promoter Systems AAV Vector Production Methods

Classification

Agency
USPTO
Published
April 2nd, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260092284A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254.1 Biotechnology 3254 Pharmaceutical Manufacturing
Activity scope
Biotechnology Patent Filing Gene Therapy Manufacturing Viral Vector Production
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Biotechnology Pharmaceuticals

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