Healthcare & Life Sciences

Stretch Layered Sheet, Disposable Wearing Article, and Manufacturing Method and Device

USPTO granted Patent US12599513B2 to ZUIKO CORPORATION on April 14, 2026. The patent covers a stretch layered sheet with thermal bonding between non-woven fabrics and film, featuring vents that provide air permeability in both stretched and non-stretched states. The invention also includes methods and devices for manufacturing the stretch layered sheet.

Kimberly-Clark Absorbent Article with Leak-Proof Containment Flaps

The USPTO granted Patent US12599510B2 to Kimberly-Clark Worldwide, Inc. on April 14, 2026. The patent covers an absorbent article with leak-proof containment flaps bonded using transverse ultrasonic point patterns. The invention restricts fluid leaks between bond lines while maintaining aesthetic appeal. The patent includes 20 claims and names Matthew X Majestic, Lynn Lynch, Janet E. Collins, Austin N. Pickett, Amanda L. Plump, Joseph J. Sina, and Lori A. Roocks as inventors.

Qatar University Surgical Robot Patent US12599442B2 Granted

USPTO granted Patent US12599442B2 to Qatar University on April 14, 2026, for an assistive surgical robot system for distal hole localization in intramedullary nail surgery. The patent covers a system including an imaging device, probe, robot, and computer program instructions for aligning fasteners to holes in implanted devices. The patent includes 18 claims and names three inventors.

Surgical Torque Sensor With Decision Support, Mazor Robotics

USPTO granted patent US12599441B2 to Mazor Robotics Ltd. on April 14, 2026. The patent covers a surgical system with a torque sensor for measuring power tool torque characteristics and decision support functionality. The 20-claim patent includes processors and memory for evaluating torque data and executing predetermined actions.

Multimodal Soft Tissue Imaging for Dermal Lesions

The USPTO granted patent US12599299B2 to Dentsply Sirona Inc. on April 14, 2026. The patent covers a method and device for multimodal imaging of dermal and mucosal lesions using at least two imaging modalities, including 3D scanning, with information on distance and angulation between the scanning device and the tissue. The patent contains 28 claims.

Apparatus for Cleaning a Laparoscope

USPTO granted US patent 12599297B2 to King Saud University for an apparatus designed to clean laparoscopes. The device includes a housing, fluid-moving assembly, wiping assembly, and trigger mechanism to spray cleaning fluid and wipe the transparent portion of the laparoscope housing. The patent contains 7 claims.

Systems and Methods for Detecting Physical Contact of Surgical Instrument with Patient Tissue

USPTO granted patent US12599298B2 to Intuitive Surgical Operations, Inc. on April 14, 2026. The patent covers a tissue contact detection system that monitors surgical instrument temperature during procedures to detect physical contact with patient tissue and trigger mitigation operations. The patent lists three inventors: Jonathan D. Halderman, Kayla K. Anderson, and Anqi Fan, with 17 claims covering the technology.

Robotic Surgical System with Removable Portion and Method of Disassembling Same (US12599446B2)

The USPTO granted Patent US12599446B2 to Cilag GmbH International for a robotic surgical system with a removable tool portion. The system includes a controller, surgical instrument, and tool with a disassembly feature that disconnects a portion of the instrument in response to controller instructions. The patent contains 20 claims and covers technology in CPC classifications A61B 34/32, A61B 50/30, and related surgical robotics categories.

Surgical Robotic System with Integrated Navigation

USPTO granted patent US12599447B2 to Globus Medical, Inc. for a surgical robotic system with integrated navigation and multiple surgical arms. The patent covers devices and methods for robot-assisted surgery to assist with procedures including pedicle screws and interbody implants. The patent contains 19 claims with inventors Norbert Johnson and David C. Paul.

Surgical Robotic Automation with Tracking Markers and Controlled Tool Advancement

The USPTO granted patent US12599443B2 to Globus Medical, Inc. covering surgical robotic automation with tracking markers and controlled tool advancement for implant insertion procedures. The patent includes 20 claims relating to threaded guide tubes for robotic surgical instruments and a dilator system enabling independent tool control within robotic surgical procedures.

Medical Light Source Device and Medical Observation System

USPTO granted Patent US12599296B2 to Sony Olympus Medical Solutions Inc. on April 14, 2026, for a medical light source device featuring dual light sources—a laser emitter and measurement light source for monitoring light guide connection states—and a control system that adjusts laser output based on return light analysis. The patent contains 20 claims.

ODH Advises Diet and Exercise Changes to Cut Chronic Disease and Cancer Risk

The Ohio Department of Health issued a public health advisory recommending dietary and exercise changes to reduce chronic disease and cancer risk among Ohioans. ODH Director Dr. Bruce Vanderhoff advised increasing fiber intake, reducing sugar consumption, and engaging in at least 2.5 hours of weekly cardiovascular activity. Dr. Earl Thompson IV highlighted colorectal cancer screening importance, noting approximately 5,500 new cases and 2,000 deaths annually in Ohio.

New Interactive Dashboard Displays Ohio Kindergarten Immunization Data

The Ohio Department of Health announced the launch of a new interactive dashboard displaying kindergarten immunization data on the state DataOhio Portal. The dashboard provides current vaccine rates, exemption rates, and specific vaccine information (MMR, DTaP) by county, school, and across years from 2017-2018 to 2025-26. The dashboard supports informed decision-making by school officials, parents, and policymakers to help protect children from vaccine-preventable diseases.

Inova Diagnostics Aptiva CTD Essential Controls Safety Action

ANSM published safety alert R2608798 informing medical biology laboratories of a quality control recall by Inova Diagnostics for Aptiva CTD Essential Controls used in autoimmune testing. The manufacturer's safety action letter was distributed to affected users on 14 April 2026. Laboratories should review the recalled controls and contact Inova Diagnostics directly for guidance.

Intraocular Lens Podeye Safety Notice - Field Safety Notice R2610293

ANSM has informed health establishments of a safety action implemented by the company Physiol/BVI regarding Podeye intraocular lenses. The safety action is registered under reference number R2610293. Health establishments concerned by this action should review the attached letter from Physiol/BVI dated 14/04/2026.

Biomarker Combinations for NASH and Hepatic Fibrosis Diagnosis

USPTO granted patent US12601747B2 to Bio-Rad Laboratories for biomarker combinations used to diagnose Non-Alcoholic Steatohepatitis (NASH) and hepatic fibrosis status. The patent covers methods and kits for evaluating liver conditions based on three or more biomarker levels in subjects with NAFLD or NASH.

Treating Glioblastoma Using Integrin Pathway Targeting

USPTO granted patent US12601743B2 to The Regents of the University of California for methods of treating drug-resistant glioblastoma (GBM) by targeting the integrin avb3 pathway. The patent covers diagnostic methods to determine tumor sensitivity and treatment methods for tumors identified as avb3+ and Glut3+ with specific molecular signatures. The patent contains 9 claims.

Maize Gene KRN2 and Uses Thereof Patent Grant US12600976B2

The USPTO granted Patent US12600976B2 to China Agricultural University for KRN2 gene technology controlling kernel row number in maize plants and associated molecular markers for molecular breeding applications. The patent contains 6 claims and names six inventors including Xiaohong Yang, Jiansheng Li, Wenkang Chen, Xuan Zhang, Lichun Cai, and Yirong Zhang.

National Nutrition Committee Holds Fourth Meeting in Riyadh

The National Nutrition Committee held its fourth meeting of the third session at SFDA headquarters in Riyadh, chaired by SFDA CEO H.E. Dr. Hisham S. Aljadhey. The Committee reviewed its strategic performance report covering initiatives, projects, and achievements through Q1 2026, as well as the Saudi Food Composition Tables book developed under the Nutrient Content of Foods initiative. The meeting included representatives from various government and private sector entities.

Method for Making Elastomeric Laminates

Procter & Gamble Patent, Elastomeric Laminate Manufacturing Method

Glaukos Ocular Drug Delivery Implant with Controlled Release

USPTO granted patent US12599497B2 to Glaukos Corporation on April 14, 2026, for an ocular drug delivery device with controlled drug release capabilities. The patent covers devices for treating ocular disorders through targeted administration of drugs to interior portions of the eye, with structures allowing treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber.

Heated Goggle Lens Patent US12599503B2

The USPTO granted patent US12599503B2 to UVEX ARBEITSSCHUTZ GMBH for a heated goggle lens comprising a main body with at least one transparent, electrically conductive coating and electrical contact means forming heating zones. The patent, filed January 21, 2022, contains 8 claims.

US12599502B2 - Ophthalmic Laser Surgical System with Bubble Shield for Reducing Retinal Radiation Exposure

USPTO granted patent US12599502B2 to Alcon Inc. (inventor: Zsolt Bor) for an ophthalmic laser surgical system that reduces retinal radiation exposure during floater treatment. The system uses a three-dimensional pulse pattern with a bubble shield pulse at the posterior side to form a protective bubble shield over the retina. The patent (CPC: A61F 9/008) contains 9 claims and was filed October 25, 2022.

Wound Dressing Fluid Management Patent B2

USPTO granted patent US12599504B2 to Solventum Intellectual Properties Company for a wound dressing with fluid management technology. The patent covers a multi-layer dressing system including an evaporative film layer with high moisture vapor transfer rate, a carrier film layer with holes for evaporation, a superabsorbent layer, and a wicking layer for wound fluid management. The patent was filed November 19, 2019, under application 17294580 with 13 claims.

US12599499B2 - Devices and Methods for Creating a Capsulorhexis

USPTO granted Patent US12599499B2 to inventor Michael Schaller for devices and methods used in creating a capsulorhexis, a surgical procedure on the eye's capsular bag. The patent covers a template with a tearing profile, rigid and bendable sections for transitioning between insertion and use configurations, and connecting elements for manipulating the device during surgery. The patent contains 15 claims.

Automated Image Guidance System for Ophthalmic Surgery

The USPTO granted Patent US12599498B2 to Alcon Inc. covering an automated image guidance system for ophthalmic surgery. The system automatically initializes image-guided surgery by detecting a user's eye in captured images, initiating a registration procedure, and generating overlay content for presentation via a second imaging device. The patent contains 20 claims.

Medi USA LP Compression Garment Patent US12599505B2

USPTO granted Patent US12599505B2 to Medi USA, L.P. for a compression garment designed to provide compression to body parts, particularly limbs. The garment features a tubular padded sleeve with inner and outer layers secured together to form enclosures containing plastic foam particles. The patent includes 18 claims and was filed on June 13, 2022.

Patent US12599500B2 for Ophthalmological Surgical Instrument

USPTO granted patent US12599500B2 to Università degli Studi di Cagliari on April 14, 2026, covering an ophthalmological surgical instrument with a hollow oblong body and cutting assembly featuring pivotally hinged arms, toothed rack, and pinion gear mechanism. The patent contains 14 claims and provides intellectual property protection for the medical device design.

Pre-Procedure Planning, Intra-Procedure Guidance for Biopsy and Ablation

USPTO granted Patent US12599437B2 to Covidien LP covering a system and method for navigation of a luminal network for pre-procedure planning and intra-procedure guidance during biopsy and ablation of tumors. The system uses CT image data, generates 3D models, and provides real-time catheter sensor location registration for navigation to tumors. The patent includes 20 claims and covers technology for use with or without cone-beam CT or fluoroscopic imaging.

Adjustable Marker Reference Device for Surgery (US12599440B2)

USPTO granted Patent US12599440B2 to Point Robotics Medtech Inc. for an adjustable marker reference device used to identify surgical instruments. The patent covers a device with a base, upper cover, connecting rods, markers, and a fixing button mechanism that allows controlled movement and positioning of markers for surgical navigation.

Stent End Point Locations System

USPTO granted Koninklijke Philips N.V. Patent US12599438B2 for a system and method for determining suitable end point locations for a stent using intraluminal imaging. The system includes processors configured to receive temporal sequences of intraluminal images from an imaging device and identify whether positions along a lumen represent suitable stent end points. The patent contains 19 claims.

Boston Scientific Patent US12599435B2 for Catheter Ablation Using Irreversible Electroporation

USPTO granted patent US12599435B2 to Boston Scientific Scimed, Inc. on April 14, 2026, for catheter systems and methods using pulsed DC voltage to drive irreversible electroporation for selective tissue ablation. The patent includes claims covering voltage pulse generators, electrode controllers with selection and pulse delivery modules, and methods for delivering pulsed voltage waveforms to selected electrodes.

Methods for Controlling Treatment Volumes in Pulsed Electric Field Treatments

USPTO granted Patent US12599429B2 to North Carolina State University covering methods for electrotherapy via pulsed electric field. The patent describes modifying or killing target cells while simultaneously controlling treatment volumes, thermal gradients, muscle stimulation, and immune responses through dynamically adjusted electrical pulse delivery profiles. The patent contains 20 claims.

Sirona Medical Catheter With Improved Irrigation - US12599431B2

USPTO granted Patent US12599431B2 to Sirona Medical Technologies, Inc. for a catheter with expandable and contractible fluid pathways. The invention includes an elongate body with a distal electrode, expandable members between the electrode and body distal end, an actuator for advancing and retracting the electrode, and a fluid-sealed lumen configured to expand and collapse with electrode movement. The patent contains 17 claims and covers catheters with improved irrigation capabilities for medical procedures.

Lung Tissue Navigation System

USPTO granted patent US12599439B2 to Covidien LP on April 14, 2026, for a system and method of navigating to target sites in lung tissue using an extended working channel with electromagnetic sensors integrated into an electromagnetic navigation system. The patent contains 20 claims and covers technology for determining and displaying the distance from a tool to a target site on a display device.

Apparatus and Method for Intra-Cardiac Mapping and Ablation

USPTO granted patent US12599433B2 to Kardium Inc. on April 14, 2026, covering an intra-cardiac mapping system that uses convective cooling effects of blood flow to locate heart chambers for ablation procedures to treat atrial fibrillation. The patent describes a catheter-deployed expandable net or scanning catheter that performs both cardiac mapping and ablation. The patent contains 35 claims with inventors Daniel Gelbart and Samuel Victor Lichtenstein.

Devices, Systems and Methods for Treatment of Abnormal Tissue Using Pulsed Electric Fields

USPTO granted Patent US12599432B2 to Galvanize Therapeutics, Inc. for devices, systems, and methods to treat abnormal tissue using pulsed electric field (PEF) energy. The patent covers non-thermal energy delivery that preserves extracellular matrices, blood vessels, and lymphatics while treating tumors, cysts, or diseased tissue. The 26 claims span filing date October 15, 2021, under application number 17502640.

Perivascular Nerve Denervation Catheter Patent US12599430B2

USPTO granted patent US12599430B2 to Deepqure Inc. on April 14, 2026. The patent covers a perivascular nerve denervation catheter featuring a shaft with a distal loop configured to curl around tissue and a plurality of electrodes made of two-way shape-memory alloy. The application was filed March 2, 2021, and includes 12 claims.

Force Redistribution Hindfoot Shoe Insert

The USPTO granted patent US12599494B2 to ROXILLA LLC for a force redistribution hindfoot shoe insert designed to absorb shock and redistribute forces within a user's foot and/or knee. The device includes a hindfoot insert portion with a fascia projection positioned medially between the sides and a lateral projection on the lateral side. The patent contains 22 claims and was filed on April 5, 2023.

Bi-Planar Expandable Spine Cage Patent US12599488B2

USPTO granted patent US12599488B2 to HILO INNOVATIONS, LLC for a bi-planar expandable spinal cage featuring separate sagittal and coronal balance control units. The invention allows independent adjustment of spacing distance and gradient between upper and lower structural bodies. The patent includes 7 claims and covers CPC classifications A61F 2/447 and A61F 2002/443.

Axially Compressible Bare Stent with Overlapping Wires for Aortic Treatment

USPTO granted Patent US12599492B2 to Shanghai Flowdynamics Medical Technology Co., Ltd. for an axially compressible bare stent used in aortic aneurysm and dissection treatment. The stent is formed by interleaving two wires of different diameters (20-150 μm and 150-600 μm) to achieve at least 30% metal coverage with strong radial support. Inventors are Jian Ding and Chenying Fan. The patent includes 16 claims.

Uncaging Stent Patent US12599490B2 - Elixir Medical

The USPTO granted Patent US12599490B2 to Elixir Medical Corporation for an uncaging stent technology. The patent covers a stent or luminal prosthesis with circumferential structural elements that provide high strength after deployment and allow for scaffold uncaging and luminal expansion. The patent includes 27 claims and was filed on March 3, 2023.

Biliary Stent Patent US12599491B2 Granted to BVW Holding AG

USPTO granted Patent US12599491B2 to BVW Holding AG for a biliary stent endoprosthesis featuring a polymeric coating with micropattern surface textures. The patent covers stents with inner/outer surfaces, lumens, and macropattern surface features in both expanded and contracted states. The patent includes 20 claims and names Lukas Bluecher and Michael Milbocker as inventors.

Male External Catheter with Attachment Interface Configured to Bias Against Penis

USPTO granted Patent US12599495B2 to PUREWICK CORPORATION for a male urine collection device. The patent covers a receptacle for collecting urine with movable flaps configured to bias against the penis, and a clamshell design with two halves connected by a hinge for secure attachment. The filing date was December 23, 2021, with Application No. 17645821 and 17 claims.

SG LLC Lateral Disc Replacement Implant Patent US12599487B2 Granted

USPTO granted patent US12599487B2 to SG LLC for a lateral disc replacement implant including first and second endplates, a core between the endplates, and an annulus surrounding the core. Inventors: Paul Glazer and Michael J. Milella, Jr. Application filed July 13, 2023.

Physio Tape With Inductive Heating System

The USPTO granted patent US12599496B1 to inventor Jason Fladoos for an inductive heating system integrated into physio tape. The invention includes plural pockets along the tape length housing removable heating or cooling elements, with at least one being an inductive heating element adapted to receive magnetic energy from a remote inductive heating source. The patent contains 11 claims.

Method of Deploying Intraluminal Device to Cardiac Stomach Region with Endoscopic-Laparoscopic System

USPTO granted patent US12599493B2 to BFKW, LLC for a method of deploying an intraluminal device to the cardiac region of the stomach. The invention involves trans-oral endoscopic deployment of the device with retention against the cardiac region while being fastened laparoscopically from the abdominal cavity with concurrent endoscopic visualization. The patent includes 18 claims covering both the method and the intraluminal system.

Spinal Cage Bone Screw Fixation, Patent US12599489B2, 14th Apr

The USPTO granted Patent US12599489B2 to GBS Commonwealth Co., Ltd. on April 14, 2026, covering a spinal cage fixable through bone screw insertion. The invention includes a cage body with a receiver having multiple screw holes, and a fixture that moves outward during screw insertion and inward after completion to prevent screw separation. The patent contains 8 claims.

Bone Fixation Device with Porous Architecture for Bone Ingrowth

USPTO granted Patent US12599418B2 to Paragon Advanced Technologies, Inc. for a bone fixation device featuring a plate portion and a bone wedge portion with porous architecture designed to promote bone ingrowth for fusion and osteosynthesis of bone segments. The patent includes 20 claims and covers the device, manufacturing method, and fixation kit.

Beveled Screw - US12599419B2 - Tyber Medical LLC

USPTO granted Patent US12599419B2 to Tyber Medical LLC on April 14, 2026. The patent covers a beveled screw design featuring a screw head with a bevel, an elongate shaft with a central longitudinal axis, and a tip distal from the head, for implantation into bone or bone fragments. The patent includes 13 claims and covers both the device and associated implantation methods.