Healthcare & Life Sciences

USPTO Patent Application: Small Molecule Inhibitors of KRAS Proteins for Cancer Treatment

The USPTO has published a patent application (US20260083750A1) detailing small molecule inhibitors of KRAS proteins for cancer treatment. The application describes compounds that can inhibit specific KRAS protein mutants and their potential utility as therapeutic agents for cancer.

USPTO Patent for Anti-CD123 Immunoconjugates Treating AML

The USPTO has published a patent application (US20260083749A1) for anti-CD123 immunoconjugates, such as pivekimab sunirine, for treating acute myeloid leukemia (AML). The patent covers methods of use as monotherapies or in combination with other agents to achieve remission or prepare patients for transplant.

USPTO Patent Application: Compositions for Mitochondrial Health

The USPTO has published a patent application (US20260083747A1) detailing compositions for supporting mitochondrial health using methylthioninium salts combined with other compounds. The application was filed on October 30, 2024, by inventors Darren Lopez and Dan Schmidt.

CMS Seeks Public Comment on Information Collection Activities

The Centers for Medicare & Medicaid Services (CMS) is seeking public comment on its intention to collect information from the public, as required by the Paperwork Reduction Act. This notice provides an opportunity for comment on the burden estimate and utility of proposed information collections related to Qualified Health Plan (QHP) certification and financial management.

USPTO Patent Application: Negative Pressure Wound Therapy Self-Testing

The USPTO has published a patent application (US20260083899A1) for a negative pressure wound therapy device with self-testing capabilities. The application details a system that includes a negative pressure source, valve, flow restrictor, pressure sensor, and control circuitry for performing leak, flow, or excessive pressure tests.

USPTO Patent Application for Chemical Pump Housing

The USPTO has published a patent application for a chemical pump housing designed for negative pressure systems. The application details a housing with an inner chamber and a reactor configured to consume selected gases found in air, intended for use in negative pressure therapy.

USPTO Patent for Negative Pressure Wound Therapy Canisters

The USPTO has published a new patent application, US20260083901A1, for negative pressure wound therapy canisters. The application details a canister design featuring two fluid chambers separated by a filter to manage fluids from a tissue site. This is a routine publication of a patent application.

USPTO Patent Application: Syringe Actuator Coupling Device

The USPTO has published a new patent application (US20260083902A1) detailing a device for reversibly coupling a syringe to an actuator. The application was filed by inventors Jean-Luc MORELLE, Philippe DUMONT, and Philippe BEKAERT.

USPTO Patent Application: Infusion Pump with Air Bubble Detection

The USPTO has published a patent application (US20260083903A1) for an infusion pump with an air bubble detection method. The invention utilizes an ultrasonic sensor and an imaging device to detect gas bubbles and particles in infusion fluids, aiming to enhance patient safety.

USPTO Patent Application for Infusion Catheter Hub Assembly

The USPTO has published a new patent application for an infusion catheter hub assembly. The application details a system designed for delivering fluid and includes an introducer needle for inserting catheters or sensors, with a user-removable hub and an activation mechanism.

USPTO Publishes Medical Device Patent Application

The USPTO published a new patent application (US20260083905A1) for a medical device on March 26, 2026. The application, filed by Terumo Kabushiki Kaisha, describes a medical device with a housing, a flexible sheet-shaped adhesion member, and a detachable attachment.

USPTO Patent Application: Thyroid Hormone Delivery Device

The USPTO has published a patent application (US20260083906A1) for a thyroid hormone delivery device. The application describes a subcutaneous implantable device with a microprocessor and precision pump for continuous thyroxine delivery, aiming to enhance patient compliance and metabolic control.

USPTO Patent Application for Intravenous Needle Insertion Device

The USPTO has published a new patent application (US20260083907A1) for an intravenous needle insertion device. The application was filed by inventors Eric Gokcen and Cem Gokcen on September 19, 2023, and is scheduled for publication on March 26, 2026.

USPTO Patent Application for Infusion Tubing Sets

The USPTO has published a patent application for short-range communicating infusion tubing sets. The application describes a system where infusion tubing can transmit information to a pump, allowing the pump to verify compatibility with a prescribed medication regimen before dispensing.

USPTO Patent Application: Vacuum Wound Dressing Connection Device

The USPTO has published a patent application (US20260083898A1) for a connection device designed to create a vacuum-tight fluidic connection between a vacuum wound dressing and a vacuum source. The application was filed by PAUL HARTMANN AG and includes specific structural features to prevent tube collapse under vacuum.

USPTO Patent Application for Aspiration Tubing Clip

The USPTO has published a patent application (US20260083305A1) for an aspiration tubing clip filed by Boston Scientific Scimed, Inc. The application describes a fluid system including a clamp for suction tubing used in medical devices.

USPTO Publishes Rectoscope Patent Application

The USPTO has published a new patent application, US20260083314A1, for a rectoscope designed for cavity inspection. The application, filed on May 29, 2025, details a device with a movable cover and a frangible window for controlled access.

USPTO Patent Application for Blood Draw Device Probe

The USPTO has published a new patent application, US20260083367A1, for a system designed to reduce buckling of a probe during the deployment of a blood draw device. The application details a fluid transfer device with specific components to control catheter movement and support.

USPTO Patent Application for Bipolar RF Access Device

The USPTO has published a patent application by Boston Scientific Scimed, Inc. for a bipolar RF access device with a sliding automatic shutoff cutting zone. The application details electrosurgical ablation devices designed for treating patient tissue.

USPTO Patent Application: Injection Apparatus and Method

The USPTO has published a patent application by pHi-Tech Animal Health Technologies Ltd. for an injection apparatus and method. The application details a hand-held unit, a remote control unit, and a pump designed for selecting medicament dose volumes.

USPTO Patent Application for Implantable Device Fixation for Urinary Incontinence

The USPTO has published a patent application (US20260083542A1) for an implantable device fixation mechanism designed to treat urinary incontinence. The application details a device with a conduit, an adjustable membrane for coaptation of a body lumen, and a fixation mechanism that can anchor or release the device using a push wire.

USPTO Patent Application for Stent Positioning Apparatus

The USPTO has published a patent application (US20260083580A1) for a stent positioning apparatus designed for use at the ostium of a blood vessel. The application details methods and apparatuses for precise stent placement, including an ostial positioning catheter with specific components.

USPTO Patent Application: Negative Pressure Wound Therapy Dressing System

The USPTO has published a patent application (US20260083596A1) for a negative pressure wound therapy (NPWT) dressing system. The application details a non-compressible, non-collapsible dressing with large-diameter passageways for suction and irrigation, designed for customizable and disposable use.

USPTO Patent Application: CBD for SYNGAP1 Encephalopathy

The USPTO has published a patent application (US20260083758A1) from Harmony Biosciences Management, Inc. detailing methods for treating SYNGAP1 encephalopathy using transdermal cannabidiol (CBD). The application was filed on November 28, 2025, and published on March 26, 2026.

USPTO Patent Application: System to Monitor Respiration During Sedation

The USPTO has published a patent application for a system designed to monitor patient respiration during sedation using nasal pressure and oxygen flow. The application details a method for identifying breathing patterns and delivering controlled oxygen pulses to ensure patient safety.

USPTO Patent Application: Gas Inhalation Mask

The USPTO has published a patent application for a gas inhalation mask with a paper body and tube attachment member, assigned to NIHON KOHDEN CORPORATION. The application details a design where the tube does not directly face the subject's face when attached.

Medical Gas Retention System Patent Application

The USPTO has published a patent application (US20260083929A1) for a medical gas retention system. The application, filed on September 15, 2025, describes a system designed to prevent unintended medical gas flow.

USPTO Patent Application: Water Quantity Detection in Humidifiers

The USPTO has published a patent application from ResMed Pty Ltd for methods and apparatus to determine the quantity of water in a humidifier. The application, filed on June 24, 2025, describes indirect measurement techniques using sensors to infer water levels without necessarily requiring disposable components.

USPTO Patent Application: Relaxation System

The USPTO has published a patent application (US20260083931A1) for a relaxation system. The system incorporates a vibrator, electrodes, and a feedback generator controlled by a processing device to monitor and influence cardiac metrics for relaxation status.

USPTO Patent Application: Odor-based TMR System

The USPTO has published a new patent application (US20260083932A1) for an odor-based TMR system designed to enhance learning and memory. The application, filed by Justin Dumitrescu, describes a system comprising a fragrance and a physical delivery system.

USPTO Patent Application: Relaxation System with Scent Release

The USPTO has published a patent application (US20260083933A1) for a relaxation system that includes a vibrator and a scent release mechanism. The application, filed by inventors Daniel Shuter, Angela Sun, and David Shuter, details a device controlled by a processing unit to manage both vibration and scent release.

USPTO Patent Application: Electronic Device for Sleep Induction Auditory Feedback

The USPTO has published a patent application (US20260083934A1) for an electronic device and method designed to provide auditory feedback for sleep induction based on a user's breathing patterns. The application details a system that synchronizes sounds with inhalation and exhalation periods.

Medical Device Reduces Friction Patent Application

The USPTO has published a patent application (US20260083940A1) for a medical device designed to reduce friction between contacting components by creating a lubricating barrier. The application was filed on September 17, 2025, by inventors Andrew James Schaubhut, Scott E. Brechbiel, and Ryan V. Wales.

USPTO Patent Application: Urinary Catheter Treatment

The USPTO has published a patent application (US20260083941A1) for a urinary catheter treatment involving a nitric oxide generating solution. The application details a method for mixing an S-nitrosothiol powder with a liquid carrier to create the solution, which is then introduced into a catheter balloon.

USPTO Patent Application: Non-occluding Balloon Catheter for Cardiovascular Drug Delivery

The USPTO has published a patent application for a non-occluding balloon catheter device designed for cardiovascular drug delivery. The application details a device that allows blood flow to continue through a bypass lumen while a drug coating is applied to the vessel wall. This innovation aims to improve drug delivery efficacy in cardiovascular treatments.

USPTO Patent Application for Clot Treatment Device

The USPTO has published patent application US20260083944A1 for a clot treatment system, including a balloon catheter with an inflation control device designed to reduce pressure during inflation. The application was filed on September 19, 2025, by inventors Benjamin Merritt and Jared Shimizu.

USPTO Patent Application: Medical Delivery System for Heart Valve

The USPTO has published a new patent application (US20260083446A1) for a medical delivery system designed for accessing and repairing a heart valve. The application was filed by Evalve, Inc. and details a system involving multiple steerable guide catheters.

USPTO Patent Application for Clot Aspiration and Blood Reinfusion Systems

The USPTO has published a patent application (US20260083467A1) for clot aspiration and blood reinfusion systems. The application details devices, systems, and methods for aspirating clot material and blood from a patient's vasculature, filtering the blood, and returning it. The filing date was September 19, 2025.

USPTO Patent Application: Shockwave Balloon Catheter and Control System

The USPTO has published a patent application for a four-interface shockwave balloon catheter and its control system. The invention aims to improve surgical treatment effectiveness and safety by allowing simultaneous fluid replenishment and discharge within the balloon. The application was filed on September 24, 2024.

Terumo Kabushiki Kaisha Catheter Patent Application

The USPTO has published a patent application (US20260083881A1) by Terumo Kabushiki Kaisha for a catheter designed to resist deterioration during long-term storage. The application details specific resin compositions and additive content for the catheter tip and main body.

USPTO Patent Application: Plasma Donation System

The USPTO has published a patent application detailing a system and method for individualized plasma donation. The invention aims to collect and determine plasma volume based on donor information and demographic data, adjusting collection protocols accordingly.

USPTO Patent Application: Negative-Pressure Accessory for Instrument

The USPTO has published a new patent application (US20260083886A1) for a negative-pressure accessory designed for use with negative-pressure instruments. The application details a device that includes a cup body and a pressure-sensing module to monitor negative pressure within the cup.

VA ECMO with Pulmonary Artery Ventilation Patent Application

The USPTO has published a patent application (US20260083887A1) for a Veno-Arterial Extracorporeal Membrane Oxygenation (ECMO) system with pulmonary artery ventilation. The application, filed by CardiacAssist, Inc., describes a dual lumen drainage cannula and associated system components designed to improve patient oxygenation and left ventricle unloading.

USPTO Patent Application: Air-Powered Peritoneal Dialysis System

The USPTO has published a new patent application (US20260083888A1) for an air-powered peritoneal dialysis system with nesting containers. The application details a system comprising a cycler with an air pump, a heater housing, nesting containers, and a control unit.

USPTO Patent Application: Damping Devices for Automated Peritoneal Dialysis Systems

The USPTO has published a new patent application detailing damping devices for automated peritoneal dialysis (APD) systems. The application, filed by inventors Farrukh Usman et al., describes a device with a body, first and second membranes, and a cavity designed to control fluid dynamics within APD systems.

USPTO Patent Application: Perfusion Pump with Occlusion Detection

The USPTO has published a patent application (US20260083890A1) for a perfusion pump with automatic occlusion detection and controlled adjustment. The application details a roller pump design incorporating sensors to measure pressure and adjust roller block movement to occlude a fluid conduit.

USPTO Patent Application: Aphaeretic Biopsy System with Microfluidic Device

The USPTO has published a new patent application, US20260083891A1, filed by Astrin Biosciences, Inc. The application describes an aphaeretic biopsy system utilizing a microfluidic device to separate and capture circulating tumor cells from a patient's bloodstream.

USPTO Patent Application: Postoperative Chest Drainage Device

The USPTO has published a new patent application (US20260083894A1) for a postoperative chest drainage device. The application details a device designed to collect fluids and separate gases originating from a patient's chest. This is a standard publication of a patent application, not a final grant or rule.

USPTO Patent Application for Surgical Suction Sponge

The USPTO has published a patent application (US20260083895A1) for a novel surgical suction sponge designed to improve the removal of bodily fluids during procedures. The application details devices, systems, and methods for a removable gasket and sponge assembly intended to protect delicate tissues while enhancing suction efficiency.

USPTO Ergonomical Medical Device Handle Fluid Coupling Patent Application

The USPTO has published a patent application (US20260083896A1) for an ergonomical medical device handle with a fluid coupling, designed for procedures like Transjugular Intrahepatic Portosystemic Shunt (TIPS). The application details a telescoping assembly with a shared flush port and locking features to improve device handling and control.