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USPTO Patent Application: CBD for SYNGAP1 Encephalopathy

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Summary

The USPTO has published a patent application (US20260083758A1) from Harmony Biosciences Management, Inc. detailing methods for treating SYNGAP1 encephalopathy using transdermal cannabidiol (CBD). The application was filed on November 28, 2025, and published on March 26, 2026.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

This document is a publication of a United States Patent and Trademark Office (USPTO) patent application, specifically application US20260083758A1, filed by Harmony Biosciences Management, Inc. The application describes methods for treating SYNGAP1 encephalopathy by administering cannabidiol (CBD) transdermally to a subject. The filing date was November 28, 2025, and the publication date is March 26, 2026.

As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on regulated entities. However, it signals potential future developments in the treatment of SYNGAP1 encephalopathy and may be of interest to pharmaceutical companies, medical device manufacturers, and researchers in the neurology and rare disease space. Compliance officers should note this as a potential future product or therapeutic area.

Archived snapshot

Mar 26, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

TREATMENT OF SYNGAP1 ENCEPHALOPATHY

Application US20260083758A1 Kind: A1 Mar 26, 2026

Assignee

Harmony Biosciences Management, Inc.

Inventors

Terri Sebree, John Messenheimer, Donna Gutterman

Abstract

The present technology relates to methods of treating SYNGAP1 encephalopathy by transdermally administering an effective amount of cannabidiol (CBD) to the subject, wherein a SYNGAP1 symptom is treated in the subject.

CPC Classifications

A61K 31/658 A61M 21/02 A61P 25/08 A61P 25/28 A61M 2021/0077

Filing Date

2025-11-28

Application No.

19403384

View original document →

Named provisions

TREATMENT OF SYNGAP1 ENCEPHALOPATHY

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Last updated

Classification

Agency
USPTO
Published
March 26th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260083758A1

Who this affects

Applies to
Drug manufacturers Medical device makers Patients
Industry sector
3254 Pharmaceutical Manufacturing 3345 Medical Device Manufacturing
Activity scope
Drug Development Medical Treatment
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Research & Development
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Pharmaceuticals Medical Devices

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