NIDCD Clinical Research Center Grant Expiration Date Change

NIH Guide Funding Opportunities

Published March 31st, 2026

Detected March 31st, 2026

Summary

NIDCD issued Notice NOT-DC-26-004 announcing a change to the expiration date of PAR-25-445, the NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional). The expiration date has been moved up from June 3, 2028 to October 3, 2026, eliminating multiple future application cycles. No other changes were made to the funding opportunity announcement.

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What changed

NIDCD has revised the expiration date of PAR-25-445, the NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional), from June 3, 2028 to October 3, 2026. This change removes application cycles beyond October 2, 2026 from the NOFO's timeline, including cycles with due dates of February 2, 2027, June 2, 2027, October 1, 2027, February 2, 2028, and June 2, 2028. The notice cites that NIDCD plans to transition to a new option for supporting multi-disciplinary, collaborative team science.

Researchers and institutions currently planning applications under this P50 mechanism should accelerate their submission timelines. The final opportunity for new, renewal, resubmission, or revision applications is now October 2, 2026, with earliest start date of July 2027. Any investigators requiring the later cycles should monitor for future NIDCD announcements regarding the new team science support mechanism.

What to do next

Review current P50 grant application timelines against new October 2, 2026 deadline
Accelerate any applications planned for removed cycles (Feb 2027 onward) to earlier submission dates
Monitor NIDCD communications for future announcements on the new multi-disciplinary team science funding option

Source document (simplified)

Notice of Change: NIDCD Expiration of PAR-25-445, "NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)" Notice Number: NOT-DC-26-004

Key Dates

Release Date: March 31, 2026

Related Announcements

September 15, 2025 - NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional). See NOFO PAR-25-445.

Issued by

National Institute on Deafness and Other Communication Disorders (NIDCD)

Purpose

The purpose of this Notice is to inform the extramural community that PAR-25-445 NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional) will expire October 3, 2026. NIDCD plans to transition to a new option for supporting multi-disciplinary, collaborative team science. More details about this transition will be available in the future.

Key Dates

The NOFO currently reads:

| Application Due Dates | | | Review and Award Cycles | | |
| --- | --- | | | | |
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
| November 04, 2025 | November 04, 2025 | Not Applicable | March 2026 | May 2026 | July 2026 |
| February 02, 2026 | February 02, 2026 | Not Applicable | July 2026 | October 2026 | December 2026 |
| June 02, 2026 | June 02, 2026 | Not Applicable | November 2026 | January 2027 | April 2027 |
| October 02, 2026 | October 02, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
| February 02, 2027 | March 02, 2027 | Not Applicable | July 2027 | October 2027 | December 2027 |
| June 02, 2027 | June 02, 2027 | Not Applicable | November 2027 | January 2028 | April 2028 |
| October 01, 2027 | October 01, 2027 | Not Applicable | March 2028 | May 2028 | July 2028 |
| February 02, 2028 | February 02, 2028 | Not Applicable | July 2028 | October 2028 | December 2028 |
| June 02, 2028 | June 02, 2028 | Not Applicable | November 2028 | January 2029 | April 2029 |

Expiration Date: June 03, 2028

Revised to read:

Expiration Date: October 03, 2026

There are no other changes to this NOFO.