SPSIP Block vs Rhomboid Block for Postoperative Analgesia in Breast Cancer Surgery: Randomized Controlled Trial
ClinicalTrials.gov Studies
Summary
This ClinicalTrials.gov registry entry announces a randomized controlled trial (NCT07536867) comparing the analgesic efficacy of Serratus Posterior Superior Intercostal Plane (SPSIP) Block versus Rhomboid Intercostal Block for postoperative pain management following breast cancer surgery with axillary lymph node dissection. The primary outcome is Visual Analog Scale pain scores during the first 24 hours post-surgery. Secondary outcomes include opioid consumption, rescue analgesia requirements, block performance time, and patient satisfaction. The study is currently recruiting.
What changed
This ClinicalTrials.gov registry entry documents a new randomized controlled trial comparing two regional anesthesia techniques for breast cancer surgery patients. The trial will enroll participants undergoing mastectomy with axillary lymph node dissection and randomize them to receive either SPSIP Block or Rhomboid Intercostal Block. The study's primary endpoint is pain control efficacy measured by Visual Analog Scale at 24 hours.
For healthcare providers and clinical investigators, this registry entry indicates ongoing research into opioid-sparing analgesic techniques for breast cancer surgery. The study's secondary outcomes examining block-related complications (hematoma, pneumothorax, local anesthetic toxicity, vascular puncture, infection) and quality of recovery metrics may inform future clinical practice guidelines. This is an informational registry entry without compliance or regulatory obligations.
Archived snapshot
Apr 17, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Comparison of Serratus Posterior Superior Intercostal Plane Block and Rhomboid Intercostal Block for Postoperative Analgesia Following Breast Cancer Surgery With Axillary Lymph Node Dissection: A Randomized Controlled Trial
N/A NCT07536867 Kind: NA Apr 17, 2026
Abstract
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) and Rhomboid Intercostal Block in patients undergoing Breast Cancer Surgery With Axillary Lymph Node Dissection. The primary outcome is Visual Analog Scale (VAS) during the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block performance time, block-related and systemic side effects (hematoma, pneumothorax, local anesthetic toxicity, vascular puncture, infection), Patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire.
Conditions: Breast Cancer, Lymph Node Dissection, Postoperative Pain, Mastectomy
Interventions: Serratus posterior superior intercostal plane block, Rhomboid intercostal plane block
Related changes
Get daily alerts for ClinicalTrials.gov Studies
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from NIH/NLM.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when ClinicalTrials.gov Studies publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.