Predictors of Clinical Response After Interlaminar Cervical Epidural Steroid Injection for Cervical Radiculopathy
Summary
NIH registered a new observational retrospective cohort study (NCT07535476) on ClinicalTrials.gov to evaluate predictors of clinical response after interlaminar cervical epidural steroid injection in patients with cervical radiculopathy. The study will analyze demographic, clinical, and procedure-related variables including pain scores before and after the procedure. Enrollment is anticipated to begin April 17, 2026.
What changed
NIH registered a new observational retrospective cohort study on ClinicalTrials.gov titled 'Predictors of Clinical Response After Interlaminar Cervical Epidural Steroid Injection for Cervical Radiculopathy' (NCT07535476). The study will examine demographic, clinical, and procedure-related variables that may predict treatment response following interlaminar cervical epidural steroid injection in patients with cervical radiculopathy. Pain scores will be analyzed before and after the procedure to identify predictors of clinical outcome.
For compliance officers, this represents a clinical trial registration for a retrospective observational study on pain management procedures. Clinical investigators conducting research on spinal injection outcomes should note the study's focus on patient selection criteria and predictor identification for this commonly used treatment option for cervical radicular pain.
Archived snapshot
Apr 18, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Predictors of Clinical Response After Interlaminar Cervical Epidural Steroid Injection for Cervical Radiculopathy
Observational NCT07535476 Kind: OBSERVATIONAL Apr 17, 2026
Abstract
Cervical epidural steroid injection is a commonly used treatment option for patients with cervical radicular pain who do not improve adequately with conservative treatment. Cervical radicular pain typically radiates from the neck to the shoulder, arm, or hand and may be accompanied by numbness, weakness or changes in reflexes. The most common causes are cervical disc herniation and cervical spondylosis. By reducing inflammation around the affected nerve root, epidural steroid injection may help relieve pain and improve function. Among available techniques, the interlaminar approach is frequently preferred in the cervical region because of its technical feasibility and safety profile.
Although interlaminar cervical epidural steroid injection is widely used, treatment response varies among patients, and not all individuals experience the same degree of benefit. Identifying the factors associated with better or poorer clinical response may help improve patient selection and reduce unnecessary procedures.
This retrospective cohort study aims to evaluate clinical outcomes after interlaminar cervical epidural steroid injection in patients with cervical radiculopathy and to investigate demographic, clinical, and procedure-related variables which may predict treatment response. By analyzing pain scores before and after the procedure, this study seeks to better define the predictors of clinical outcome following this intervention.
Conditions: Radiculopathy, Cervical Region, Neck Pain, Disc Disease, Radicular Pain
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