Blood Brain Barrier Model Patent
Summary
The European Patent Office published patent application EP3494213A1 for Wake Forest University Health Sciences covering a 3D blood-brain barrier model and methods of making and using the same. The patent, filed with Robert T. Wicks, Anthony Atala, Goodwell Nzou, and Elizabeth E. Wicks listed as inventors, covers technology useful for pharmaceutical research and neurological drug development. The patent is designated for all EU member states plus several additional European countries.
What changed
The EPO published European patent application EP3494213A1 for Wake Forest University Health Sciences relating to a 3D blood-brain barrier model. The patent covers methods of creating and using an in vitro model that simulates the blood-brain barrier for drug testing and research applications. IPC classifications indicate applications in cell culture technology, organ/tissue preparations, and biological preparations related to the circulatory and nervous systems.
This is a patent grant publication rather than a regulatory action imposing compliance obligations. No deadlines, required actions, or penalties apply. Companies developing neurological drugs or conducting blood-brain barrier research should review the patent claims to assess potential licensing needs or freedom-to-operate considerations.
Source document (simplified)
BLOOD BRAIN BARRIER MODEL AND METHODS OF MAKING AND USING THE SAME
Publication EP3494213A1 Kind: A1 Mar 25, 2026
Applicants
Wake Forest University Health Sciences
Inventors
WICKS, Robert T., ATALA, Anthony, NZOU, Goodwell, WICKS, Elizabeth E.
IPC Classifications
C12N 5/079 20100101AFI20191205BHEP C12N 5/0797 20100101ALI20191205BHEP A61K 35/44 20150101ALI20191205BHEP A61K 35/30 20150101ALI20191205BHEP C12N 5/0793 20100101ALI20191205BHEP C12N 5/071 20100101ALI20191205BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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