Changeflow GovPing Pharma & Drug Safety Blood Brain Barrier Model Patent
Routine Notice Added Final

Blood Brain Barrier Model Patent

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP3494213A1 for Wake Forest University Health Sciences covering a 3D blood-brain barrier model and methods of making and using the same. The patent, filed with Robert T. Wicks, Anthony Atala, Goodwell Nzou, and Elizabeth E. Wicks listed as inventors, covers technology useful for pharmaceutical research and neurological drug development. The patent is designated for all EU member states plus several additional European countries.

What changed

The EPO published European patent application EP3494213A1 for Wake Forest University Health Sciences relating to a 3D blood-brain barrier model. The patent covers methods of creating and using an in vitro model that simulates the blood-brain barrier for drug testing and research applications. IPC classifications indicate applications in cell culture technology, organ/tissue preparations, and biological preparations related to the circulatory and nervous systems.

This is a patent grant publication rather than a regulatory action imposing compliance obligations. No deadlines, required actions, or penalties apply. Companies developing neurological drugs or conducting blood-brain barrier research should review the patent claims to assess potential licensing needs or freedom-to-operate considerations.

Source document (simplified)

← EPO Patent Bulletin

BLOOD BRAIN BARRIER MODEL AND METHODS OF MAKING AND USING THE SAME

Publication EP3494213A1 Kind: A1 Mar 25, 2026

Applicants

Wake Forest University Health Sciences

Inventors

WICKS, Robert T., ATALA, Anthony, NZOU, Goodwell, WICKS, Elizabeth E.

IPC Classifications

C12N 5/079 20100101AFI20191205BHEP C12N 5/0797 20100101ALI20191205BHEP A61K 35/44 20150101ALI20191205BHEP A61K 35/30 20150101ALI20191205BHEP C12N 5/0793 20100101ALI20191205BHEP C12N 5/071 20100101ALI20191205BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP3494213A1

Who this affects

Applies to
Healthcare providers Medical device makers Pharmaceutical companies
Industry sector
3254.1 Biotechnology 3254 Pharmaceutical Manufacturing 3345 Medical Device Manufacturing
Activity scope
Biotechnology Research Pharmaceutical Development
Geographic scope
European Union EU

Taxonomy

Primary area
Healthcare
Operational domain
Legal
Topics
Biotechnology Intellectual Property

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