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FNDC5 Patent for Neurological Disorders Treatment - Dana-Farber

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP3052137A1 filed by Dana-Farber Cancer Institute, Inc. covering compositions and methods for identifying, assessing, preventing, and treating neurological disorders and diseases using FNDC5. The application names Bruce M. Spiegelman and Christiane D. WRANN as inventors and includes International Patent Classifications A61K 38/17 and related therapeutic categories.

What changed

EPO published European patent application EP3052137A1 (A1 publication with search report) for Dana-Farber Cancer Institute covering FNDC5-based compositions and methods for neurological disorder treatment. The application claims therapeutic uses, pharmaceutical compositions, and diagnostic applications relating to the FNDC5 protein. The patent designates all EPC contracting states including DE, FR, GB, IT, NL, ES, and others.

Pharmaceutical companies and biotechnology firms conducting research on FNDC5, irisin, or related neurological therapies should review this application to assess potential freedom-to-operate implications. Healthcare researchers studying exercise-induced neurological benefits should monitor the patent prosecution timeline. The patent has not yet been granted; third parties may file observations or opposition once granted.

What to do next

  1. Review patent claims for FNDC5-related products and assess freedom-to-operate exposure
  2. Monitor prosecution status of EP3052137A1 for claim scope and geographic coverage
  3. Evaluate whether ongoing or planned research activities may be affected by potential exclusive rights

Source document (simplified)

← EPO Patent Bulletin

IDENTIFICATION, ASSESSMENT, PREVENTION, AND TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES USING FNDC5

Publication EP3052137A1 Kind: A1 Mar 25, 2026

Applicants

Dana-Farber Cancer Institute, Inc.

Inventors

SPIEGELMAN, Bruce M., WRANN, Christiane D.

IPC Classifications

A61K 38/17 20060101AFI20170412BHEP A61K 48/00 20060101ALI20170412BHEP G01N 33/50 20060101ALI20170412BHEP C12Q 1/68 20060101ALI20170412BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
EP3052137A1

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Researchers
Industry sector
3254 Pharmaceutical Manufacturing 6211 Healthcare Providers 3254.1 Biotechnology
Activity scope
Pharmaceutical patents Biotechnology patents Medical treatment patents
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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