Trolox-peptide conjugate and use thereof
Summary
USPTO issued Patent Grant US12589064B2 to Caregen Co., Ltd. on March 31, 2026, covering a Trolox-peptide conjugate for hair loss prevention. The patented compound inhibits 5α-reductase activity, prevents papilla cell and keratinocyte death, promotes cell growth, and provides antioxidant effects. The patent contains 9 claims and names Yong Ji Chung, Eun Mi Kim, Eung Ji Lee, and Min Woong Kim as inventors.
What changed
The USPTO granted Patent US12589064B2 to Caregen Co., Ltd. for a Trolox-peptide conjugate with hair loss prevention applications. The patent (Application No. 17607115, filed May 6, 2020) claims a compound where Trolox and a peptide are chemically bonded, effective at inhibiting 5α-reductase, preventing cell death, promoting growth, and providing antioxidant activity. The grant confers exclusive intellectual property rights to the assignee.
Regulated entities do not need to take immediate compliance actions based on this patent grant. However, pharmaceutical and biotechnology companies developing hair loss treatments or 5α-reductase inhibitors should review this patent to assess potential freedom-to-operate concerns. Companies should ensure their R&D activities do not infringe on the granted claims and should consult with IP counsel regarding licensing opportunities if commercializing related products.
Source document (simplified)
Trolox-peptide conjugate and use thereof
Grant US12589064B2 Kind: B2 Mar 31, 2026
Assignee
Caregen Co., Ltd.
Inventors
Yong Ji Chung, Eun Mi Kim, Eung Ji Lee, Min Woong Kim
Abstract
The present invention relates to a Trolox-peptide conjugate having a structure in which Trolox and a peptide are chemically bonded. The Trolox-peptide conjugate not only very effectively inhibits the activity of 5α-reductase, but also inhibits the death of papilla cells and keratinocytes, promotes the growth thereof, and has antioxidative effects, and thus can remarkably promote hair formation while avoiding or preventing hair loss.
CPC Classifications
A61K 8/498 A61K 47/64 A61K 8/64 A61P 17/14 A61Q 7/00 C07K 7/06 C07K 7/08
Filing Date
2020-05-06
Application No.
17607115
Claims
9
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