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USPTO Patent Application: Neurodegenerative Disorder Treatment

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Published May 16th, 2025
Detected March 26th, 2026
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Summary

The USPTO has published a new patent application (US20260083766A1) detailing methods for treating neurodegenerative disorders by modulating RNA editing. The application was filed on May 16, 2025, by inventors Nandkishore Raghav Belur and Joseph Robert Mazzulli.

What changed

This document is a USPTO patent application (US20260083766A1) for methods to treat neurodegenerative disorders by reducing nuclear aggregates and modulating adenosine-to-inosine RNA editing. The application, filed on May 16, 2025, by inventors Nandkishore Raghav Belur and Joseph Robert Mazzulli, describes administering adenosine-to-inosine editing modifiers to restore neuronal synaptic function.

As this is a patent application, it does not impose direct regulatory obligations or compliance deadlines on companies. However, it signals potential future developments in pharmaceutical research and development for neurodegenerative diseases. Companies in the pharmaceutical and biotechnology sectors may wish to monitor the progress of this application and related intellectual property.

Source document (simplified)

← USPTO Patent Applications

METHODS TO TREAT NEURODEGENERATIVE DISORDERS BY REDUCING NUCLEAR AGGREGATES AND MODULATING ADENOSINE-TO-INOSINE RNA EDITING

Application US20260083766A1 Kind: A1 Mar 26, 2026

Inventors

Nandkishore Raghav Belur, Joseph Robert Mazzulli

Abstract

This disclosure provides methods for treating neurodegenerative diseases and restoring neuronal synaptic function by administering adenosine-to-inosine editing modifiers.

CPC Classifications

A61K 31/7064 A61P 25/16 A61P 25/28 C12N 15/113 C12N 2310/11

Filing Date

2025-05-16

Application No.

19211071

View original document →

Named provisions

Abstract Inventors CPC Classifications

Classification

Agency
USPTO
Published
May 16th, 2025
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260083766A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Drug Development RNA Editing Modulation
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
R&D
Topics
Biotechnology Medical Research

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