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Patent Application: Synergistic Stimulation for Cystic Fibrosis Mucus Obstruction

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Published September 19th, 2023
Detected March 26th, 2026
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Summary

The USPTO has published a new patent application (US20260083698A1) detailing methods for treating mucus obstruction in cystic fibrosis and other disorders. The application, filed on September 19, 2023, describes a combination therapy involving a b-adrenergic agonist or adenylate cyclase activator with a cholinergic agonist.

What changed

This document is a patent application (US20260083698A1) filed with the USPTO on September 19, 2023. It describes a novel therapeutic method for treating muco-obstructive disorders, specifically cystic fibrosis, by administering a combination of a b-adrenergic agonist or adenylate cyclase activator and a cholinergic agonist. The application details the synergistic stimulation of mucociliary clearance as the mechanism of action.

While patent applications are not regulations, they indicate potential future developments in pharmaceutical treatments. Companies involved in drug development for respiratory diseases, particularly cystic fibrosis, should be aware of this patented technology. Compliance officers in the pharmaceutical sector should monitor the progression of this patent and similar research, as it may influence future product development and regulatory submissions in the area of muco-obstructive disorder treatments.

Source document (simplified)

← USPTO Patent Applications

Synergistic Stimulation of Mucociliary Clearance to Treat Mucus Obstruction in Cystic Fibrosis and Other Muco-Obstructive Disorders

Application US20260083698A1 Kind: A1 Mar 26, 2026

Inventors

Jeffrey J. Wine, Nam Soo Joo, Carlos E. Milla

Abstract

The present disclosure provides methods of treating an individual for a muco-obstructive, the methods including: administering to the individual a b-adrenergic agonist or an adenylate cyclase activator, in combination with a cholinergic agonist to treat the individual for the muco-obstructive disorder.

CPC Classifications

A61K 31/352 A61K 31/27 A61P 11/12

Filing Date

2023-09-19

Application No.

19110980

View original document →

Classification

Agency
USPTO
Published
September 19th, 2023
Instrument
Guidance
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260083698A1

Who this affects

Applies to
Drug manufacturers Patients Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Therapeutic Treatment
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Research & Development
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Medical Devices Public Health

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