Changeflow GovPing Pharma & Drug Safety Sotorasib Dosing Regimen Patent Application
Routine Notice Added Final

Sotorasib Dosing Regimen Patent Application

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Published December 16th, 2022
Detected March 26th, 2026
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Summary

The USPTO has received a patent application (US20260083741A1) for a sotorasib dosing regimen. The application, filed by Brett E. Houk and Panli Cardona, details methods for administering sotorasib to patients, particularly those with KRAS G12C-mutated cancer who also require treatment with a BCRP substrate like rosuvastatin.

What changed

The United States Patent and Trademark Office (USPTO) has published a patent application, identified as US20260083741A1, concerning a specific dosing regimen for the drug sotorasib. The application, filed on December 16, 2022, by inventors Brett E. Houk and Panli Cardona, outlines methods for administering sotorasib to patients diagnosed with cancer that includes a KRAS G12C mutation. A key aspect of the disclosure is its applicability to patients who are also undergoing treatment with a breast cancer resistance protein (BCRP) substrate, such as rosuvastatin.

This filing represents a new patent application related to pharmaceutical treatments. While patent applications do not impose direct compliance obligations on regulated entities, they are crucial for understanding future intellectual property landscapes and potential market exclusivity for specific drug formulations or administration methods. Companies involved in the development, manufacturing, or marketing of sotorasib or related therapies should monitor the progress of this patent application as it could impact future commercialization strategies and competitive dynamics within the oncology sector.

Source document (simplified)

← USPTO Patent Applications

SOTORASIB DOSING REGIMEN

Application US20260083741A1 Kind: A1 Mar 26, 2026

Inventors

Brett E. Houk, Panli Cardona

Abstract

The present disclosure provides method of administering sotorasib to a patient, e.g., a patient with a cancer comprising a KRAS G12C mutation, wherein the patient is further in need of treatment with a breast cancer resistance protein (BCRP) substrate. e.g., rosuvastatin.

CPC Classifications

A61K 31/519 A61K 31/505

Filing Date

2022-12-16

Application No.

19112616

View original document →

Classification

Agency
USPTO
Published
December 16th, 2022
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260083741A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Patent Filing
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Intellectual Property Drug Development

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