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USPTO Patent Application for Indoline Derivatives as Serotonergic Agents

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Summary

The USPTO has published a patent application (US20260083703A1) for indoline derivatives intended for use as serotonergic agents. The application details potential treatments for disorders related to serotonin receptor activation, including psychosis, mental illnesses, and CNS disorders.

What changed

This document is a publication of a United States Patent and Trademark Office (USPTO) patent application, specifically application number US20260083703A1, filed on April 18, 2023. The application, titled 'INDOLINE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO,' describes novel indoline derivatives, their preparation, compositions containing them, and their use in activating serotonin receptors. The intended therapeutic applications include the treatment of psychosis, mental illnesses, and central nervous system (CNS) disorders.

As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on regulated entities. However, it signals potential future developments in pharmaceutical research and development within the specified therapeutic areas. Companies involved in drug discovery and development, particularly those focusing on neurological and psychiatric disorders, should be aware of this application as it may indicate emerging intellectual property in the field.

Source document (simplified)

← USPTO Patent Applications

INDOLINE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO

Application US20260083703A1 Kind: A1 Mar 26, 2026

Inventors

Abdelmalik SLASSI, Joseph A. ARAUJO

Abstract

The present application relates to indoline derivatives of general Formula (I), to processes for their preparation, to compositions comprising them and to their use in activation of a serotonin receptors in a cell, as well as to treating diseases, disorders or conditions by activation of a serotonin receptors in a cell. The diseases, disorders or conditions include, for example, psychosis, mental illnesses and CNS disorders and/or associated endophenotypes and/or symptom clusters. Wherein Q is selected from (Q1), (Q2), (Q2′), (Q4) and (Q5).

CPC Classifications

A61K 31/404 A61K 31/407 A61K 31/427 A61K 31/4439 A61K 31/454 C07B 59/002 C07D 401/04 C07D 401/14 C07D 403/04 C07D 403/06 C07D 405/14 C07D 409/14 C07D 417/14 C07D 491/056 C07B 2200/05

Filing Date

2023-04-18

Application No.

18857234

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Classification

Agency
USPTO
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260083703A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Pharmaceutical Research
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Drug Development Medical Research

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