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Reduced Dosing Regimens for Glaucoma Treatment Methods

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Published March 26th, 2026
Detected March 26th, 2026
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Summary

The USPTO has published a patent application (US20260083746A1) detailing methods for treating open-angle glaucoma by transitioning patients to a once-daily dosing regimen. The proposed treatment involves a pharmaceutical composition containing timolol, brimonidine, dorzolamide, and bimatoprost.

What changed

This document is a USPTO patent application (US20260083746A1) for a reduced dosing regimen for glaucoma treatment. The application describes methods for treating open-angle glaucoma by administering a pharmaceutical composition containing timolol, brimonidine, dorzolamide, and bimatoprost once per day, transitioning patients from more frequent dosing schedules.

As this is a patent application, it does not impose direct regulatory obligations on pharmaceutical companies or healthcare providers. However, it signals potential future developments in glaucoma treatment that may impact product development and clinical practice guidelines. Companies involved in glaucoma therapeutics should monitor the progress of this patent application and related innovations.

Source document (simplified)

← USPTO Patent Applications

REDUCED DOSING REGIMENS FOR GLAUCOMA TREATMENT

Application US20260083746A1 Kind: A1 Mar 26, 2026

Inventors

Dennis Elias Saadeh

Abstract

Methods for treating open-angle glaucoma include transitioning a patient from a twice-per-day or more treatment regimen to a once-per-day treatment regimen. The once-per-day treatment include administering a single dose of a pharmaceutical composition including timolol or a pharmaceutically acceptable salt thereof, brimonidine or a pharmaceutically acceptable salt thereof, dorzolamide or a pharmaceutically acceptable salt thereof, and bimatoprost or a pharmaceutically acceptable salt thereof, once per day.

CPC Classifications

A61K 31/5377 A61K 9/0048 A61K 31/382 A61K 31/498 A61K 31/5575 A61K 47/02 A61K 47/10 A61K 47/12 A61K 47/26 A61P 27/06

Filing Date

2025-09-25

Application No.

19339566

View original document →

Named provisions

REDUCED DOSING REGIMENS FOR GLAUCOMA TREATMENT

Classification

Agency
USPTO
Published
March 26th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260083746A1

Who this affects

Applies to
Drug manufacturers Healthcare providers Patients
Industry sector
3254 Pharmaceutical Manufacturing 6211 Healthcare Providers
Activity scope
Drug Labeling Clinical Trial Reporting
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Research & Development
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Medical Devices Healthcare

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