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PLGA Nanoparticles with CAPE Drug and Angiopep-2 Peptide for Cancer Treatment

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Published March 25th, 2026
Detected April 2nd, 2026
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Summary

The European Patent Office published patent application EP4167955A1 filed by Yildiz Teknik Universitesi for a drug composition comprising PLGA nanoparticles loaded with CAPE (caffeic acid phenethyl ester) and targeted with Angiopep-2 peptide for cancer treatment. The application names inventors Derman, Mansuroglu, Bozkurt, Acar, and Sayan Poyraz. No compliance deadlines or obligations are associated with this patent publication.

What changed

The EPO published patent application EP4167955A1 covering a PLGA nanoparticle drug delivery system loaded with CAPE and functionalized with Angiopep-2 peptide for targeted cancer therapy. The application claims priority to IPC classifications A61K 9/00, A61P 35/00, A61K 9/51, A61K 45/06, and A61K 35/644, with designated states covering all major European jurisdictions.

This is a patent publication notice with no compliance obligations or deadlines. Pharmaceutical companies, drug manufacturers, and healthcare entities involved in nanoparticle-based cancer therapeutics or targeted drug delivery should review the claims to assess potential freedom-to-operate considerations or licensing opportunities.

Source document (simplified)

← EPO Patent Bulletin

DRUG COMPRISING PLGA NANOPARTICLES LOADED WITH CAPE TARGETED WITH ANGIOPEP-2 PEPTIDE

Publication EP4167955A1 Kind: A1 Mar 25, 2026

Applicants

Yildiz Teknik Universitesi

Inventors

DERMAN, Serap, MANSUROGLU, Banu, BOZKURT, Yagmur, ACAR, Tayfun, SAYAN POYRAZ, Fatma

IPC Classifications

A61K 9/00 20060101AFI20211224BHEP A61P 35/00 20060101ALI20211224BHEP A61K 9/51 20060101ALI20211224BHEP A61K 45/06 20060101ALI20211224BHEP A61K 35/644 20150101ALI20211224BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP4167955A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Pharmaceutical Manufacturing
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Intellectual Property
Topics
Healthcare Intellectual Property

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