Heterocyclic BLT2 Agonist Compounds and Medical Use
Summary
The European Patent Office published patent application EP4545138A1 for heterocyclic compounds acting as BLT2 (leukotriene B4 receptor 2) agonists filed by Fraunhofer-Gesellschaft and Goethe University Frankfurt. The patent covers the compounds, pharmaceutical compositions, and their medical use primarily for dermatological conditions and pain management. The filing includes five inventors: Hernandez-Olmos, Heering, Proschak, Steinhilber, and Weigert.
What changed
EPO published patent EP4545138A1 granting protection for heterocyclic BLT2 agonist compounds and their medical applications. The patent names Fraunhofer-Gesellschaft and Goethe University Frankfurt as applicants, with designated states covering 38 European countries including Germany, France, UK, Italy, Spain, and other EPO member states. The compounds are classified under multiple C07D heterocyclic categories and are intended for dermatological (A61P 17/00) and analgesic (A61P 29/00) applications.
This is a routine patent publication that creates intellectual property rights rather than regulatory obligations. Pharmaceutical companies developing BLT2-targeted therapies should conduct freedom-to-operate analyses to assess potential infringement risks. No compliance actions or deadlines apply to this publication. Competitors seeking to develop similar compounds will need to either license the technology or design around the claims.
Source document (simplified)
HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE
Publication EP4545138A1 Kind: A1 Mar 25, 2026
Applicants
Fraunhofer-Gesellschaft zur Förderung
der angewandten Forschung e.V., Johann-Wolfgang-Goethe-Universität
Frankfurt am Main
Inventors
Hernandez-Olmos, Victor, Heering, Jan, Proschak, Eugen, Steinhilber, Dieter, Weigert, Andreas
IPC Classifications
A61P 17/00 20060101AFI20240319BHEP A61P 29/00 20060101ALI20240319BHEP C07D 209/44 20060101ALI20240319BHEP C07D 403/10 20060101ALI20240319BHEP C07D 403/14 20060101ALI20240319BHEP C07D 413/14 20060101ALI20240319BHEP C07D 417/14 20060101ALI20240319BHEP C07D 471/10 20060101ALI20240319BHEP C07D 487/10 20060101ALI20240319BHEP A61K 31/4045 20060101ALI20240319BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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