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Routine Notice Added Final

Heterocyclic BLT2 Agonist Compounds and Medical Use

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Published March 25th, 2026
Detected April 2nd, 2026
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Summary

The European Patent Office published patent application EP4545138A1 for heterocyclic compounds acting as BLT2 (leukotriene B4 receptor 2) agonists filed by Fraunhofer-Gesellschaft and Goethe University Frankfurt. The patent covers the compounds, pharmaceutical compositions, and their medical use primarily for dermatological conditions and pain management. The filing includes five inventors: Hernandez-Olmos, Heering, Proschak, Steinhilber, and Weigert.

What changed

EPO published patent EP4545138A1 granting protection for heterocyclic BLT2 agonist compounds and their medical applications. The patent names Fraunhofer-Gesellschaft and Goethe University Frankfurt as applicants, with designated states covering 38 European countries including Germany, France, UK, Italy, Spain, and other EPO member states. The compounds are classified under multiple C07D heterocyclic categories and are intended for dermatological (A61P 17/00) and analgesic (A61P 29/00) applications.

This is a routine patent publication that creates intellectual property rights rather than regulatory obligations. Pharmaceutical companies developing BLT2-targeted therapies should conduct freedom-to-operate analyses to assess potential infringement risks. No compliance actions or deadlines apply to this publication. Competitors seeking to develop similar compounds will need to either license the technology or design around the claims.

Source document (simplified)

← EPO Patent Bulletin

HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE

Publication EP4545138A1 Kind: A1 Mar 25, 2026

Applicants

Fraunhofer-Gesellschaft zur Förderung
der angewandten Forschung e.V., Johann-Wolfgang-Goethe-Universität
Frankfurt am Main

Inventors

Hernandez-Olmos, Victor, Heering, Jan, Proschak, Eugen, Steinhilber, Dieter, Weigert, Andreas

IPC Classifications

A61P 17/00 20060101AFI20240319BHEP A61P 29/00 20060101ALI20240319BHEP C07D 209/44 20060101ALI20240319BHEP C07D 403/10 20060101ALI20240319BHEP C07D 403/14 20060101ALI20240319BHEP C07D 413/14 20060101ALI20240319BHEP C07D 417/14 20060101ALI20240319BHEP C07D 471/10 20060101ALI20240319BHEP C07D 487/10 20060101ALI20240319BHEP A61K 31/4045 20060101ALI20240319BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

BLT2 Agonists Medical Use Pharmaceutical Compositions

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP4545138A1

Who this affects

Applies to
Pharmaceutical companies Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Pharmaceutical Patent Filing Drug Compound Patent Medical Use Patent
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Intellectual Property Healthcare

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