Salts and Solid Forms of Piperidine-2,6-Dione for Treating Disorders
Summary
USPTO published patent application US20260098035A1 on April 9, 2026, covering novel salts and solid forms of (S)- or racemic 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione. Inventors Lianfeng HUANG, Daozhong ZOU, and Tsz Chung LAI filed the application on September 19, 2023, claiming pharmaceutical compositions for treating, preventing, and managing various disorders.
What changed
USPTO published patent application US20260098035A1 covering novel salts and solid forms of a specific piperidine-2,6-dione compound (CPC: C07D 413/14), with claims to pharmaceutical compositions and methods of treating various disorders.
Implications: Pharmaceutical companies developing or commercializing piperidine-based therapeutics should conduct patent landscape analysis to assess freedom-to-operate risks. Competitors may need to design around this patent or seek licensing arrangements. The publication date of April 9, 2026 establishes prior art for subsequent applications in this chemical space.
What to do next
- Monitor patent prosecution status for US20260098035A1
- Assess freedom-to-operate implications for competing piperidine compound developers
- Evaluate potential licensing or patent clearance requirements
Archived snapshot
Apr 9, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
SALTS AND SOLID FORMS OF (S)- OR RACEMIC 3-(4-((4-(MORPHOLINOMETHYL)BENZYL)OXY)-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE AND METHODS OF USING THE SAME
Application US20260098035A1 Kind: A1 Apr 09, 2026
Inventors
Lianfeng HUANG, Daozhong ZOU, Tsz Chung LAI
Abstract
Provided herein are salts of and solid forms comprising free base or salts of (S)- or racemic 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione. Pharmaceutical compositions comprising such salts and solid forms and methods of use of such salts and solid forms for treating, preventing, and managing various disorders are also provided herein.
CPC Classifications
C07D 413/14 A61K 31/5377 A61K 31/573 C07C 55/10 C07C 59/06 C07C 59/08 C07C 59/265 C07C 59/50 C07K 16/2896 C07B 2200/13
Filing Date
2023-09-19
Application No.
19113397
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