Patent Application for On-Board Lysis Capsule in Fluidic Cartridge

ChangeBridge: Patent Apps - Biotech (C12N)

Published March 26th, 2026

Detected March 27th, 2026

Summary

The USPTO has published a patent application (US20260085275A1) for an on-board lysis capsule designed for fluidic cartridges. The capsule contains beads and magnetic elements for cell lysis and may include an internal control for assay validation. The application was filed by Gen-Probe Incorporated.

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What changed

This document is a published patent application from the USPTO detailing an "On-Board Lysis Capsule in a Fluidic Cartridge." The invention, assigned to Gen-Probe Incorporated, features a hollow body with porous membranes containing non-magnetic beads and at least one magnetic element. This capsule is designed to perform cell lysis procedures within a fluidic cartridge, potentially including an internal control to validate assay results and lysis effectiveness.

As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on entities. However, it signifies potential future technological developments in the biotechnology and medical device sectors. Companies involved in developing diagnostic kits or fluidic systems should be aware of this patent filing as it may relate to their intellectual property landscape or future product development.

Source document (simplified)

← USPTO Patent Applications

CAPSULE FOR ON-BOARD LYSIS IN A FLUIDIC CARTRIDGE

Application US20260085275A1 Kind: A1 Mar 26, 2026

Assignee

Gen-Probe Incorporated

Inventors

Byron J. KNIGHT, Norbert D. HAGEN, David OPALSKY, Daniel J. SOLIS

Abstract

A lysis capsule for performing a cell lysis procedure includes a hollow body having an open first end and an open second end, a first porous membrane covering the open first end, and a second porous membrane covering the open second end, and the hollow body defines a lysis chamber between the first and second porous membranes. A plurality of non-magnetic beads and at least one magnetic element are disposed within the lysis chamber, and the pores of the first and second porous membranes are sized to retain the non-magnetic beads and the magnetic element within the lysis chamber. An internal control may be contained within the lysis chamber to validate an assay result and/or to validate the effectiveness of the cell lysis procedure. The lysis capsule may be disposed within a sample chamber of a fluidic cartridge.