Patent Application for Engineered Bacteriophage Transducing Particles Production
Summary
The USPTO has published a new patent application (US20260083787A1) from TROBIX BIO LTD. for systems and methods for producing engineered bacteriophage transducing particles. The application details novel approaches for manipulating bacterial populations using these particles and associated regulatory elements.
What changed
This document is a publication of a new patent application filed by TROBIX BIO LTD. The application, titled "SYSTEMS FOR PRODUCTION OF TRANSDUCING PARTICLES, METHODS, KITS, COMPOSITIONS AND USES THEREOF," describes novel systems and methods for producing engineered bacteriophage transducing particles. These particles are designed to manipulate bacterial populations by expressing specific nucleic acid sequences, utilizing a protective regulated array and specific regulators.
As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on entities. However, it signifies potential future developments in biotechnology and pharmaceutical research. Companies operating in the biotechnology and pharmaceutical sectors, particularly those involved in gene therapy, antimicrobial development, or genetic engineering of bacteria, should be aware of this filing as it may indicate emerging technologies or intellectual property in the field.
Source document (simplified)
SYSTEMS FOR PRODUCTION OF TRANSDUCING PARTICLES, METHODS, KITS, COMPOSITIONS AND USES THEREOF
Application US20260083787A1 Kind: A1 Mar 26, 2026
Assignee
TROBIX BIO LTD.
Inventors
Adi ELKELES, Ziv LIFSHITZ, Yaron FELDHEIM, Lirit DUCHOVNI, Ehud QIMRON, Ido YOSEF
Abstract
The present disclosure provides improved systems and methods for production of bacteriophage-based engineered transducing particles and uses thereof in manipulating bacterial populations to express any nucleic acid sequence of interest. The disclosed systems are based on inserting to producing cells nucleic acid molecules that comprise the nucleic acid sequence of interest and a protective regulated array, and regulators specific for the regulator array. The system further provides helper transducing particle that facilitates the propagation of the transducing particle.
CPC Classifications
A61K 35/76 A61P 31/04 C12N 9/224 C12N 15/111 C12N 15/74 C12N 2310/20 C12N 2795/10033 C12N 2795/10043 C12N 2800/40 C12N 2830/006
Filing Date
2023-09-05
Application No.
19109066
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