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Patent Application for Engineered Bacteriophage Transducing Particles Production

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Summary

The USPTO has published a new patent application (US20260083787A1) from TROBIX BIO LTD. for systems and methods for producing engineered bacteriophage transducing particles. The application details novel approaches for manipulating bacterial populations using these particles and associated regulatory elements.

What changed

This document is a publication of a new patent application filed by TROBIX BIO LTD. The application, titled "SYSTEMS FOR PRODUCTION OF TRANSDUCING PARTICLES, METHODS, KITS, COMPOSITIONS AND USES THEREOF," describes novel systems and methods for producing engineered bacteriophage transducing particles. These particles are designed to manipulate bacterial populations by expressing specific nucleic acid sequences, utilizing a protective regulated array and specific regulators.

As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on entities. However, it signifies potential future developments in biotechnology and pharmaceutical research. Companies operating in the biotechnology and pharmaceutical sectors, particularly those involved in gene therapy, antimicrobial development, or genetic engineering of bacteria, should be aware of this filing as it may indicate emerging technologies or intellectual property in the field.

Source document (simplified)

← USPTO Patent Applications

SYSTEMS FOR PRODUCTION OF TRANSDUCING PARTICLES, METHODS, KITS, COMPOSITIONS AND USES THEREOF

Application US20260083787A1 Kind: A1 Mar 26, 2026

Assignee

TROBIX BIO LTD.

Inventors

Adi ELKELES, Ziv LIFSHITZ, Yaron FELDHEIM, Lirit DUCHOVNI, Ehud QIMRON, Ido YOSEF

Abstract

The present disclosure provides improved systems and methods for production of bacteriophage-based engineered transducing particles and uses thereof in manipulating bacterial populations to express any nucleic acid sequence of interest. The disclosed systems are based on inserting to producing cells nucleic acid molecules that comprise the nucleic acid sequence of interest and a protective regulated array, and regulators specific for the regulator array. The system further provides helper transducing particle that facilitates the propagation of the transducing particle.

CPC Classifications

A61K 35/76 A61P 31/04 C12N 9/224 C12N 15/111 C12N 15/74 C12N 2310/20 C12N 2795/10033 C12N 2795/10043 C12N 2800/40 C12N 2830/006

Filing Date

2023-09-05

Application No.

19109066

View original document →

Named provisions

Abstract Assignee Inventors

Classification

Agency
USPTO
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260083787A1
Docket
19109066

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Biotechnology Research Genetic Engineering
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Biotechnology Intellectual Property

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