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Complement Factor B-modulating compositions and methods of use thereof

Grant US12595477B2 Kind: B2 Apr 07, 2026

Assignee

ADARx Pharmaceuticals, Inc.

Inventors

Zhen Li, Rui Zhu, Zhiqing (Joel) Zhou, Sean Studer, Kimberly Fultz, Jean da Silva Correia

Abstract

Aspects of the disclosure provide compounds, compositions, and methods for modulating the expression or activity of Complement Factor B (CFB). In certain aspects, the compounds, compositions, and methods of the disclosure can be used to reduce the expression of CFB mRNA in a cell or animal. In certain aspects, the compounds, compositions, and methods of the disclosure can be used to reduce the expression of CFB protein in a cell or animal.

CPC Classifications

C12N 15/11

Filing Date

2022-11-23

Application No.

18058664

Claims

19

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