Complement Factor B-modulating compositions and methods of use thereof
Grant
US12595477B2
Kind: B2
Apr 07, 2026
Assignee
ADARx Pharmaceuticals, Inc.
Inventors
Zhen Li, Rui Zhu, Zhiqing (Joel) Zhou, Sean Studer, Kimberly Fultz, Jean da Silva Correia
Abstract
Aspects of the disclosure provide compounds, compositions, and methods for modulating the expression or activity of Complement Factor B (CFB). In certain aspects, the compounds, compositions, and methods of the disclosure can be used to reduce the expression of CFB mRNA in a cell or animal. In certain aspects, the compounds, compositions, and methods of the disclosure can be used to reduce the expression of CFB protein in a cell or animal.
CPC Classifications
C12N 15/11
Filing Date
2022-11-23
Application No.
18058664
Claims
19