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DANISCO US Inc. Modified Yeast Over-Expressing GDS1 for Ethanol Production

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Summary

The USPTO granted patent US12606599B2 to DANISCO US Inc. on April 21, 2026, covering modified yeast strains that over-express the glycerol-deficient suppressor GDS1. The patented yeast produces increased ethanol and decreased acetate compared to parental cells, making it suitable for large-scale ethanol production from starch substrates where acetate is undesirable. The patent names Zhongqiang Chen, Min Qi, Luan Tao, and Quinn Qun Zhu as inventors and covers compositions and methods for industrial fermentation applications.

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What changed

The USPTO granted patent US12606599B2 to DANISCO US Inc. on April 21, 2026, covering modified yeast strains that over-express the glycerol-deficient suppressor GDS1. The invention increases ethanol yield while reducing acetate byproduct compared to parental yeast strains.

Biofuel producers, fermentation companies, and industrial biotechnology firms should be aware of this intellectual property protection. DANISCO US Inc. now holds exclusive rights to this yeast modification technology for large-scale ethanol production from starch substrates, which could affect licensing negotiations and competitive positioning in the biofuel and industrial fermentation sectors.

Archived snapshot

Apr 21, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Over-expression of GDS1 in yeast for increased ethanol and decreased acetate production

Grant US12606599B2 Kind: B2 Apr 21, 2026

Assignee

DANISCO US INC.

Inventors

Zhongqiang Chen, Min Qi, Luan Tao, Quinn Qun Zhu

Abstract

Described are compositions and methods relating to modified yeast that over-express the glycerol-deficient suppressor, GDS1. The yeast produces an increased amount of ethanol and a deceased amount of acetate compared to parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates where acetate in an undesirable end product.

CPC Classifications

C07K 14/395 C12N 1/16 C12N 9/16 C12P 7/06 C12P 7/54 Y02E 50/10

Filing Date

2023-02-16

Application No.

18170454

Claims

12

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Last updated

Classification

Agency
USPTO
Published
April 21st, 2026
Instrument
Rule
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Manufacturers
Industry sector
3254.1 Biotechnology
Activity scope
Patent grant Intellectual property protection Industrial fermentation
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Energy Biotechnology

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