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Mitochondria-enriched Genetically Engineered Cells and Uses Thereof

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Summary

The USPTO granted Patent No. US12605410B2 to Minovia Therapeutics Ltd. covering pharmaceutical compositions of mitochondrially-enriched genetically engineered T cells and methods of using such cells to treat diseases and disorders. The patent, with 18 claims, was filed on March 30, 2021. This IP grant gives Minovia enforceable rights to its cell engineering technology through the patent term.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

The USPTO issued Patent No. US12605410B2 to Minovia Therapeutics Ltd., covering pharmaceutical compositions containing mitochondrially-enriched genetically engineered T cells and methods of treatment using such cells. The patent includes 18 claims across multiple CPC classifications spanning immunology, genetic engineering, and oncology applications.

Pharmaceutical and biotechnology companies developing engineered cell therapies should review this patent when designing similar T cell or immunotherapy programs. Freedom-to-operate analyses for cell engineering technologies should account for this granted IP. The patent provides Minovia with enforceable exclusivity for the specified compositions and treatment methods through the patent term.

Archived snapshot

Apr 21, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Mitochondria-enriched genetically engineered cells and uses thereof

Grant US12605410B2 Kind: B2 Apr 21, 2026

Assignee

Minovia Therapeutics Ltd.

Inventors

Natalie Yivgi-Ohana, Noa Sher, Moriya Blumkin, Elad Jacoby

Abstract

The present invention is based on the discovery that cells enriched with mitochondria are useful for treating diseases and disorders. Disclosed are pharmaceutical compositions of mitochondrially-enriched genetically engineered T cells and methods of treatment using mitochondrially-enriched genetically engineered T cells.

CPC Classifications

A61K 35/545 A61K 38/1774 A61K 40/11 A61K 40/31 A61K 40/4211 A61K 35/28 A61K 35/17 A61K 2039/5156 A61K 39/0011 C12N 5/0636 C12N 15/86 C12N 2502/025 C12N 2740/10043 C12N 2510/00 A61P 35/00 C07K 14/7051

Filing Date

2021-03-30

Application No.

17910304

Claims

18

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Last updated

Classification

Agency
USPTO
Published
April 21st, 2026
Instrument
Rule
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12605410B2

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254.1 Biotechnology
Activity scope
Patent grant Intellectual property
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Biotechnology

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