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ENGINZYME AB Biocatalyst CPS Silica Patent US12606812B2

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Summary

USPTO granted patent US12606812B2 to ENGINZYME AB on April 21, 2026, covering a biocatalyst composition for organic synthesis. The invention comprises controlled porosity silica (CPS) as support material with pore diameters between 20 and 100 nm, an amino-functionalized surface, and one or more immobilized catalytically active enzymes. The patent includes three claims and covers methods of manufacture and uses.

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What changed

USPTO granted ENGINZYME AB patent US12606812B2 for a biocatalyst composition comprising controlled porosity silica (CPS) as support material with pore diameters between 20 and 100 nm, an amino-functionalized surface, and immobilized catalytically active enzymes. The patent also covers methods of manufacturing such biocatalysts and uses thereof in organic synthesis. The patent contains 3 claims and was granted on April 21, 2026, with an application date of November 19, 2024.

Biotechnology and pharmaceutical manufacturers developing enzyme-based processes for organic synthesis should review this patent when considering enzyme immobilization technologies using porous silica supports in the specified pore size range. The patent may be relevant to companies engaged in biocatalysis research, enzyme engineering, or sustainable manufacturing processes. COMP entry via CPC classifications C12N 11/14, C12N 9/20, C12N 11/06, and C12Y 301/01003 indicates applicability to enzyme immobilization and lipase-based biocatalytic processes.

Archived snapshot

Apr 21, 2026

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← USPTO Patent Grants

Biocatalysts for organic synthesis

Grant US12606812B2 Kind: B2 Apr 21, 2026

Assignee

ENGINZYME AB

Inventors

Natalia Alvarenga Da Silva, Elin Stridfeldt, Alexey Volkov, Federica Ruggieri, Peter Hendil-Forssell, Carl Rämgård, Thomas Baumgarten, Ashley Mattey, Vince Murphy, Matthew P. Thompson, Alden M. Clemments, Sebastian Gergel

Abstract

The invention relates to a biocatalyst for organic synthesis, comprising a controlled porosity silica (CPS) as support material, wherein the pore diameter is between about 20 and about 100 nm, said support material comprising an amino-functionalized surface; and one or more catalytically active enzyme(s) immobilized on the support material. The invention also relates to uses of such biocatalysts and methods of manufacture thereof.

CPC Classifications

C12N 11/14 C12N 9/20 C12N 11/06 C12Y 301/01003

Filing Date

2024-11-19

Application No.

18951938

Claims

3

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Last updated

Classification

Agency
USPTO
Published
April 21st, 2026
Instrument
Notice
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12606812B2

Who this affects

Applies to
Manufacturers
Industry sector
3254.1 Biotechnology
Activity scope
Patent granting Enzyme immobilization Biocatalyst manufacturing
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Biotechnology Pharmaceuticals

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