Microfluidic Device for Mimicking Three-Dimensional Tissue Barrier
Summary
USPTO published patent application US20260109925A1 filed by Yong Tae Kim and Hoon Suk Rho on May 27, 2024, covering a microfluidic device designed to mimic in vivo tissue barriers using 2D-3D, 3D, and 3D-3D connective tissue barrier structures. The invention aims to serve as an alternative to animal models for new drug development and toxicity assessment applications.
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GovPing monitors USPTO Patent Applications - Biotech (C12N) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 263 changes logged to date.
What changed
USPTO published patent application US20260109925A1 disclosing a microfluidic device engineered to replicate the structure and function of in vivo tissue barriers, including 2D-3D connective tissue barriers, 3D tissue barriers, and 3D-3D tissue barriers. The application claims the device can serve as a replacement for animal models in drug development pipelines and toxicity assessment workflows.
Affected parties include researchers in drug development, pharmaceutical companies conducting toxicity testing, and biotechnology firms developing organ-on-a-chip or in vitro tissue models. The publication represents a procedural milestone in the patent examination process but does not itself grant enforceable patent rights or impose compliance obligations.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
MICROFLUIDIC DEVICE FOR FORMING THREE-DIMENSIONAL TISSUE BARRIER
Application US20260109925A1 Kind: A1 Apr 23, 2026
Inventors
Yong Tae KIM, Hoon Suk Rho
Abstract
The present invention relates to a microfluidic device for mimicking the structure and function of an in vivo tissue barrier. Specifically, the present invention relates to a microfluidic device which replaces an animal model by mimicking the structure and function of a 2D-3D connective tissue barrier, a 3D tissue barrier, and a 3D-3D tissue barrier, and thus may be used as a model for new drug development and toxicity assessment, a method for culturing cells in the microfluidic device, and a method for mimicking an organ or a tissue using the microfluidic device.
CPC Classifications
C12M 21/08 C12M 23/16 C12M 25/04 C12N 5/0697 C12N 2513/00
Filing Date
2024-05-27
Application No.
19475370
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