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IAPP Peptides Inhibit Human Amyloid Polypeptide Aggregation

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Summary

The USPTO published patent application US20260109744A1 for amyloid peptide variants developed by inventors David Moffet and Luiza Nogaj. The application covers IAPP peptides designed to inhibit aggregation of human Islet Amyloid Polypeptide and their use in preventing amyloid fibril formation. The application was filed on December 17, 2025, under application number 19423936, and received CPC classifications C07K 14/4711, A61P 5/50, and A61K 38/00.

“IAPP peptides which inhibit the aggregation of human Islet Amyloid Polypeptide and their use in inhibiting amyloid fibril formation.”

USPTO , verbatim from source
Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

About this source

USPTO classification C07K covers peptides: short amino-acid chains that form the backbone of antibodies, hormones, vaccines, and increasingly a wider class of therapeutic modalities. Every newly published application in C07K lands in this feed, around 175 a month. Applications publish 18 months after filing, so this feed reveals what antibody engineering groups, vaccine developers, and plant biotech researchers were working on in the prior year and a half. Watch this if you compete in biologics, file freedom-to-operate analyses on antibody drug candidates, scout acquisition targets in vaccine platforms, or track protein-based agricultural biotech filings.

What changed

The USPTO published patent application US20260109744A1 covering amyloid peptide variants that inhibit human Islet Amyloid Polypeptide aggregation. The application, filed by inventors David Moffet and Luiza Nogaj on December 17, 2025, describes IAPP peptides designed to prevent amyloid fibril formation with potential therapeutic applications for amyloid-related diseases.

This patent application publication does not create any compliance obligations for pharmaceutical or biotechnology companies. Organizations developing amyloid-targeting therapeutics or diagnostics may wish to monitor this application's prosecution for potential freedom-to-operate considerations, though the mere publication of a patent application does not constitute a granted exclusive right.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

AMYLOID PEPTIDE VARIANTS

Application US20260109744A1 Kind: A1 Apr 23, 2026

Inventors

David Moffet, Luiza Nogaj

Abstract

IAPP peptides which inhibit the aggregation of human Islet Amyloid Polypeptide and their use in inhibiting amyloid fibril formation.

CPC Classifications

C07K 14/4711 A61P 5/50 A61K 38/00

Filing Date

2025-12-17

Application No.

19423936

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Medical device makers Healthcare providers
Industry sector
3254.1 Biotechnology
Activity scope
Patent application Biotechnology research Therapeutic development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare Medical Devices

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