CRISPR Cpf1 for Acidithiobacillus Ferrooxidans Genes
Summary
Columbia University (The Trustees of Columbia University in the City of New York) has filed a published patent application (US20260109942A1) with the USPTO covering methods and genomic editing systems for Acidithiobacillus ferrooxidans using Cpf1 (Cas12a). The application was filed on October 31, 2025 and published on April 23, 2026. Inventors include Scott Banta, Heejung Jung, and Yuta Inaba.
About this source
GovPing monitors USPTO Patent Applications - Biotech (C12N) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 227 changes logged to date.
What changed
The published patent application discloses methods and genomic editing systems for Acidithiobacillus ferrooxidans leveraging Cpf1 (Cas12a) endonuclease technology. The application covers CRISPR-based gene knockdown approaches specific to this chemolithoautotrophic bacterium.
Biotechnology companies and research institutions working on extremophile genome engineering, bioleaching applications, or CRISPR-Cpf1 systems for industrial microorganisms should review this filing for potential freedom-to-operate implications. The breadth of the claims regarding Cpf1 use in A. ferrooxidans may affect similar research programs or commercial applications in biomining and environmental biotechnology.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
CRISPR KNOCKDOWN OT ACIDITHIOBACILLUS FERROOXIDANS GENES
Application US20260109942A1 Kind: A1 Apr 23, 2026
Assignee
The Trustees of Columbia University in the City of New York
Inventors
SCOTT BANTA, HEEJUNG JUNG, YUTA INABA
Abstract
Methods and genomic editing systems for Acidithiobacillus ferrooxidans are described herein involving use of Cpf1 (Cas12a).
CPC Classifications
C12N 1/20 C12N 9/226 C12N 15/113 C12N 15/74 C12N 2310/20 C12N 2310/531 C12R 2001/01
Filing Date
2025-10-31
Application No.
19376033
Mentioned entities
Parties
Related changes
Get daily alerts for USPTO Patent Applications - Biotech (C12N)
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from USPTO.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when USPTO Patent Applications - Biotech (C12N) publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.