Changeflow GovPing Pharma & Life Sciences

Recent changes

GovPing monitors 142 sources for this role across Guidance, Enforcement, Rule, Notice, and Consultation, out of 2,503 total sources on the platform. The past week saw 602 changes across these sources.

FDA issued a Warning Letter to Purolea Cosmetics Lab for CGMP violations, while also warning Dry Springs Pharmacy for unlawful opioid sales. A Class I recall of Philips Trilogy Evo ventilators highlights a serious device safety issue. The Class I recall of Draeger Atlan A350 anesthesia workstations further underscores critical equipment risks.

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CD8-specific capture agents, compositions, and methods of using and making

The USPTO granted Regeneron Pharmaceuticals patent US12594350B2 covering stable peptide-based CD8 capture agents for use as detection agents. The patent was issued April 7, 2026, naming Regeneron Pharmaceuticals, Inc. as assignee and Heather Dawn Agnew and Bert Tsunyin Lai as inventors. The application, filed April 4, 2017 (Application No. 15478596), contains 13 claims.

Routine Notice Intellectual Property
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Virus-like Particles Patent Granted to University of Denver

The USPTO granted Patent US12594329B2 to the University of Denver on April 7, 2026. The patent covers virus-like particles, compositions, antibody detection tests using virus-like particles, and methods of producing non-replicating virus-like particles from modified viral genomes. Schuyler B. van Engelenburg is the sole inventor of the 9-claim patent.

Routine Notice Intellectual Property
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Temperature-Optimized Bacillus Strains Patent Grant

The USPTO granted patent US12593849B2 to Chr. Hansen A/S on April 7, 2026, covering new strains of Bacillus paralicheniformis with improved growth rates and plant growth promoting properties. The patent names six inventors including Patricia Dominguez Cuevas and Lars Moelbak, with 21 claims. Filing date was August 28, 2020, under application number 17638152.

Routine Notice Intellectual Property
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HIV Oral Drug Composition Patent

The USPTO granted Patent US12594244B2 to Gilead Sciences, Inc. covering a solid oral dosage form combining tenofovir alafenamide, emtricitabine, and a compound of Formula I for HIV treatment. The patent contains 29 claims and was granted on April 7, 2026, with a filing date of September 29, 2025.

Routine Notice Pharmaceuticals
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Topiramate oral liquid suspension patent granted

USPTO granted patent US12594241B2 to inventors Paul Sudhakar and Scott Boyer for an oral liquid suspension formulation containing topiramate (Application No. 18462651). The patent contains 29 claims covering the composition and methods of medical treatment using the formulation. Generic and branded pharmaceutical manufacturers should assess this patent for potential freedom-to-operate implications.

Routine Notice Intellectual Property
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Nanoparticulate drug delivery for therapeutic applications

The USPTO granted Patent US12594347B2 to Duke University for compositions comprising self-assembling conjugates designed for nanoparticulate drug delivery. The patent covers conjugates with albumin binding domains and molecules having log D ≥ 1.5 at pH 7.4, intended for therapeutic applications including cancer treatment (A61P 35/00). Assignee: Duke University; Inventors: Parisa Yousefpour, Ashutosh Chilkoti.

Routine Notice Intellectual Property
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Exosome Production Method for Cancer Therapeutic Delivery

USPTO granted patent US12594344B2 to China Medical University for a large-scale exosome production method using cyclic tensile bioreactors. The patent covers exosomes with anti-HLA-G protein configured as delivery vehicles for cancer therapeutic agents. The grant includes 10 claims and applies to A61P 35/00 (antineoplastic agents) and related CPC classifications.

Routine Rule Intellectual Property
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Probiotics to prevent cognitive dysfunction

USPTO granted patent US12593863B2 to INTERNATIONAL N&H DENMARK APS covering the use of Lacticaseibacillus paracasei bacteria for preventing or treating cognitive impairments, including those induced by sleep deprivation. The patent names Sile Griffin, Elaine Patterson, and Markus Lehtinen as inventors and includes 5 claims.

Routine Notice Intellectual Property
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Cisplatin-Eugenol Analogue for Cancer Treatment

The USPTO granted Patent US12594338B2 to King Faisal Specialist Hospital & Research Centre for a cisplatin-eugenol compound with anti-cancer properties. The patent covers the compound composition, synthesis method, pharmaceutical formulations, and methods of cancer treatment. Inventors include Abdelilah Aboussekhra, Ibrahim Al-Jammaz, Basem Al-Otaibi, and Noura N. Alraouji. The patent was filed on July 27, 2023.

Routine Notice Pharmaceuticals
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Bioactive benzocycloheptene analogues as PI3K/MK2 inhibitors

USPTO granted Patent US12595234B2 to the Council of Scientific & Industrial Research for bioactive benzocycloheptene analogues that inhibit PI3K and MK2. The patent covers compounds for treating type 2 diabetes, inflammatory conditions, epilepsy, cancer, and CNS disorders. The patent contains 10 claims.

Routine Notice Intellectual Property

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Filters

142 official sources tracked

Regs.gov: Food and Drug Administration

Updated 4m ago

USPTO Trademarks - Pharmaceuticals (Class 005)

Updated 11d ago

USPTO Patent Applications - Pharma (A61K)

Updated 2d ago

USPTO Patent Applications - Biotech (C12N)

Updated 17h ago

ClinicalTrials.gov

Updated 24m ago

USPTO Patent Applications - Peptides (C07K)

Updated 2d ago

USPTO Patent Applications - Organic Chemistry (C07D)

Updated 4d ago

USPTO Patent Applications - Therapeutics (A61P)

Updated 2d ago

USPTO Patent Grants - Therapeutics (A61P)

Updated 19m ago

USPTO Patent Grants - Organic Chemistry (C07D)

Updated 12h ago

USPTO Patent Grants - Peptides (C07K)

Updated 7h ago

ANSM Drug & Device Safety Alerts

Updated 4m ago

FDA: Drug Recalls Class II

Updated 8d ago

FR: National Institutes of Health

Updated 33m ago

Health Canada Recalls & Safety Alerts

Updated 6m ago

Regs.gov: Centers for Medicare and Medicaid Services

Updated 22h ago

FR: Health and Human Services Department

Updated 15m ago

FR: Food and Drug Administration

Updated 33m ago

FDA Warning Letters

Updated 3m ago

CPSC Product Recalls

Updated 13d ago

FR: Drug Enforcement Administration

Updated 12d ago

MHRA Guidance & Safety

Updated 32m ago

WHO News

Updated 3h ago

CMS Newsroom

Updated 5d ago

FR: Centers for Disease Control and Prevention

Updated 1d ago

FR: Centers for Medicare & Medicaid Services

Updated 17m ago

Regs.gov: Occupational Safety and Health Administration

Updated 20h ago

DEA Press Releases

Updated 27m ago

EPO Patent Bulletin - Pharma (A61K)

Updated 23m ago

HSA Singapore Announcements

Updated 22m ago

FDA Medical Device Recalls

Updated 1m ago

DEA Public Safety Alerts

Updated 6d ago

Regs.gov: Animal and Plant Health Inspection Service

Updated 5d ago

FDA Recalls & Safety Alerts

Updated 17h ago

Regs.gov: Centers for Disease Control and Prevention

Updated 23h ago

Saudi SFDA News

Updated 21h ago

Regs.gov: Food Safety and Inspection Service

Updated 11d ago

HHS OIG Reports & Publications

Updated 12d ago

FR: Health Resources and Services Administration

Updated 6m ago

ANSM France News

Updated 11m ago

FDA Press Releases

Updated 24h ago

WV Board of Pharmacy

Updated 10d ago

USP Compendial Notices

Updated 12d ago

NH Board of Pharmacy Actions

Updated 12d ago

BfArM Drug Safety Communications

Updated 3d ago

EPO Patent Bulletin - Therapeutics (A61P)

Updated 37m ago

PMPRB

Updated 25m ago

MS Board of Pharmacy News

Updated 27d ago

LA Board of Pharmacy News

Updated 27d ago

UK VMD

Updated 19m ago

FDA Debarment List

Updated 9d ago

FDA Drug Recalls Class I

Updated 19d ago

FDA AI-Enabled Medical Devices

Updated 23d ago

GA Board of Pharmacy Board Orders

Updated 22d ago

KS Board of Pharmacy Newsletters

Updated 20d ago

NICE Technology Appraisals

Updated 7d ago

FDA Guidance Documents

Updated 3h ago

ECHA News

Updated 14d ago

WI Pharmacy Board Newsletters

Updated 26d ago

FDA Untitled Letters

Updated 23d ago

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Regulatory affairs professionals, pharmacovigilance teams, and medical affairs groups at pharma companies and CROs who need to track FDA and EMA actions.

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