Cisplatin-Eugenol Analogue for Cancer Treatment
Summary
The USPTO granted Patent US12594338B2 to King Faisal Specialist Hospital & Research Centre for a cisplatin-eugenol compound with anti-cancer properties. The patent covers the compound composition, synthesis method, pharmaceutical formulations, and methods of cancer treatment. Inventors include Abdelilah Aboussekhra, Ibrahim Al-Jammaz, Basem Al-Otaibi, and Noura N. Alraouji. The patent was filed on July 27, 2023.
What changed
The USPTO granted patent protection for a novel cisplatin analogue combined with eugenol, a compound derived from clove oil, demonstrating enhanced anti-cancer activity. The patent (US12594338B2) covers the chemical compound itself, its synthesis process, pharmaceutical compositions containing the compound, and methods of treating cancer using the compound. CPC classifications include C07F 15/0093 (platinum compounds), A61P 35/00 (antineoplastic agents), and A61K 47/54 (drug conjugates). The patent contains 2 claims.
Pharmaceutical companies and research institutions engaged in oncology drug development should review this patent to assess potential licensing opportunities or to ensure freedom-to-operate for related cancer therapeutics research. Academic medical centers and drug developers working on platinum-based chemotherapy improvements may find this intellectual property relevant to their programs. No immediate compliance action is required as patent grants do not impose regulatory obligations on third parties.
Source document (simplified)
Cisplatin analogue with potent anti-cancer effects and synthesis thereof
Grant US12594338B2 Kind: B2 Apr 07, 2026
Assignee
King Faisal Specialist Hospital & Research Centre
Inventors
Abdelilah Aboussekhra, Ibrahim Al-Jammaz, Basem Al-Otaibi, Noura N. Alraouji
Abstract
The present invention relates to a compound comprising a cisplatin component and a eugenol component. The present invention further relates to a synthesis method of said compound, pharmaceutical compositions comprising the compound and its medical uses. The present invention further relates to a method of treatment of cancer.
CPC Classifications
C07F 15/0093 A61P 35/00 A61K 47/54
Filing Date
2023-07-27
Application No.
18227094
Claims
2
Named provisions
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