Changeflow GovPing Pharma & Drug Safety Cisplatin-Eugenol Analogue for Cancer Treatment
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Cisplatin-Eugenol Analogue for Cancer Treatment

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Published April 7th, 2026
Detected April 7th, 2026
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Summary

The USPTO granted Patent US12594338B2 to King Faisal Specialist Hospital & Research Centre for a cisplatin-eugenol compound with anti-cancer properties. The patent covers the compound composition, synthesis method, pharmaceutical formulations, and methods of cancer treatment. Inventors include Abdelilah Aboussekhra, Ibrahim Al-Jammaz, Basem Al-Otaibi, and Noura N. Alraouji. The patent was filed on July 27, 2023.

What changed

The USPTO granted patent protection for a novel cisplatin analogue combined with eugenol, a compound derived from clove oil, demonstrating enhanced anti-cancer activity. The patent (US12594338B2) covers the chemical compound itself, its synthesis process, pharmaceutical compositions containing the compound, and methods of treating cancer using the compound. CPC classifications include C07F 15/0093 (platinum compounds), A61P 35/00 (antineoplastic agents), and A61K 47/54 (drug conjugates). The patent contains 2 claims.

Pharmaceutical companies and research institutions engaged in oncology drug development should review this patent to assess potential licensing opportunities or to ensure freedom-to-operate for related cancer therapeutics research. Academic medical centers and drug developers working on platinum-based chemotherapy improvements may find this intellectual property relevant to their programs. No immediate compliance action is required as patent grants do not impose regulatory obligations on third parties.

Source document (simplified)

← USPTO Patent Grants

Cisplatin analogue with potent anti-cancer effects and synthesis thereof

Grant US12594338B2 Kind: B2 Apr 07, 2026

Assignee

King Faisal Specialist Hospital & Research Centre

Inventors

Abdelilah Aboussekhra, Ibrahim Al-Jammaz, Basem Al-Otaibi, Noura N. Alraouji

Abstract

The present invention relates to a compound comprising a cisplatin component and a eugenol component. The present invention further relates to a synthesis method of said compound, pharmaceutical compositions comprising the compound and its medical uses. The present invention further relates to a method of treatment of cancer.

CPC Classifications

C07F 15/0093 A61P 35/00 A61K 47/54

Filing Date

2023-07-27

Application No.

18227094

Claims

2

View original document →

Named provisions

Abstract Claims CPC Classifications Filing Date Application No.

Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12594338B2

Who this affects

Applies to
Pharmaceutical companies Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Cancer Research
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Intellectual Property
Topics
Healthcare Intellectual Property

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