Healthcare & Life Sciences

Get Ahead Colorado Texts Coloradans Free Tax Credits

The Colorado Department of Public Health and Environment's Get Ahead Colorado campaign announced it will send text messages to Colorado residents informing them about free tax support and various tax credits. Messages will promote the Child Tax Credit, Colorado Family Affordability Tax Credit, and Earned Income Tax Credit. The campaign directs eligible taxpayers earning $89,000 or less to free filing assistance at GetYourRefund.org.

Compound Emulsion Injection for Nausea and Vomiting

The USPTO published patent application US20260097042A1 for a compound emulsion combining aprepitant and palonosetron hydrochloride for injection. The formulation claims improved stability and enhanced patient adherence in preventing and treating nausea and vomiting. The application was filed on May 30, 2025.

Compositions and Methods for IV Administration of ABDNAZ for Cancer Treatment

USPTO published patent application US20260097013A1 for compositions and methods for intravenous administration of ABDNAZ (2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone) for cancer treatment. The application, filed on 2025-06-11, covers formulations containing autologous whole blood and ABDNAZ for rapid IV infusion. Inventors: Bryan T. Oronsky, Jan Scicinski, and Scott Caroen.

Pressure Balancing Across Microfluidic Devices

USPTO published patent application US20260097163A1 by Astrin Biosciences, Inc. The application covers an aphaeretic biopsy system using microfluidic devices with inertial separation techniques to extract released tumor cells from patient bloodstream. The system includes a removable cartridge with stacked microfluidic devices implementing pressure balancing to distribute blood evenly across devices for improved separation performance.

Percutaneous AVF Creation Using Catheters with Electric Field Alignment

USPTO published patent application US20260096833A1 for a method and apparatus for percutaneous creation of arteriovenous fistula (AVF) using catheters with asymmetric electric field alignment detection. The invention is intended for vascular access in hemodialysis patients. The application includes claims covering catheter-based AVF creation methods and alignment detection systems.

Self-Current-Generating Skin-Applicable Patch Comprising Biodegradable Metal

USPTO published patent application US20260097198A1 for a self-current-generating skin-applicable patch comprising biodegradable metal. The patch includes first and second electrode layers and a support layer with ionic solution, enabling iontophoresis and micro-current effects without external power. Application 19112970 was filed September 20, 2023.

Absorbable Anastomotic Protection Device and Fecal Diversion Device for Post-Colorectal Surgery

USPTO published patent application US20260096819A1 for an absorbable anastomotic protection and fecal diversion device for colorectal surgery. Inventors include Jing Lu, Yong Zhang, Jie Shao, and Zicai Zhu. The device comprises a fecal diversion device with inflatable flushing section, balloon air tubes, cleaning tube, intestinal protective film, supporting balloons, and absorbable elastic band made of absorbable polymer material.

Compounds and Combinations Thereof for Treating Neurological and Psychiatric Conditions

The USPTO published patent application US20260097006A1 by inventor Herriot Tabuteau, filed September 4, 2025, covering compounds and combinations containing dextromethorphan for treating neurological and psychiatric conditions. The application discloses dosage forms and drug delivery systems typically combined with antidepressants such as bupropion. This publication makes the application publicly available for review and potential opposition.

Epoxytiglienone Compounds for Disrupting Gram-negative Bacterial Biofilms

The USPTO has published patent application US20260097011A1 for epoxytiglienone compounds designed to disrupt biofilms comprising Gram-negative bacteria. The application covers methods of dispersing established biofilms through localized administration, including topical or injection delivery, as well as methods for preventing biofilm formation on medical devices. Inventors include David William Thomas, Paul Warren Reddell, Glen Mathew Boyle, and others. The application was filed on December 2, 2025.

Plumbing and Backflow Training - April 14, 2026 - Franklin IN

The Indiana Department of Health announces a plumbing and backflow training event scheduled for April 14, 2026 from 8:30am to 3:00pm EDT at the Johnson County Purdue Extension office in Franklin, IN. The training is organized by the Johnson County Health Department and interested parties should RSVP to Andrew Miller, Environmental Health Specialist.

One-Way Bronchus Valve with Integrated Support, Lower Cost

USPTO published Patent Application US20260096886A1 by inventors Gang HOU, Ting YANG, and Chen WANG for a one-way valve for bronchus with an integrated support portion and air-permeable portion. The application claims the design reduces production costs compared to prior art nickel-titanium alloy frameworks while increasing yield rates. The application was filed September 19, 2023, under Application No. 19115289.

Battery Powered Heated Eye Mask, Cordless Design

USPTO published patent application US20260096921A1 for a battery-powered heated eye mask with detachable eye covers, multiple independently controllable heating zones, and steam generation capability for therapeutic treatment of meibomian gland dysfunction, blepharitis, and dry eye disease. The invention by inventor Justin Mendelson features rechargeable batteries integrated within the body portion for cordless operation.

Volkanus SRL Patent Application, Bedridden Fall Prevention Device

The USPTO published patent application US20260096915A1 by Volkanus SRL on April 9, 2026, covering a system for preventing bedridden patients from falling. The invention comprises a bed and a fall-prevention functional limitation device adapted to be wrapped around the patient, featuring a smock with cape, upper and lower pairs of side bands, and a head passage hole. The application was originally filed on September 14, 2023.

US20260096919A1 - Sleep Apnea Dental Appliance

USPTO published patent application US20260096919A1 for a dental appliance designed to treat obstructive sleep apnea or hypopnea. The application, filed December 10, 2025, by inventor Dayen Peter Wang, includes claims for both the device and a method of preparing it. CPC classifications span dental devices and health data systems.

Transcatheter Mitral Regurgitation Coaptation Device and System

The USPTO published patent application US20260096884A1 for a transcatheter mitral regurgitation treatment device. The invention covers a coaptation assistance element for implantation across the mitral valve, delivery systems including anchors and catheters, and methods for transcatheter implantation. The application was filed on October 9, 2025.

Non-Woven Fabric Mouth Tape with Integrated Silicone Gel

The USPTO published patent application US20260096918A1 for a non-woven fabric mouth tape with integrated silicone gel. The invention comprises a non-woven fabric substrate with adhesive for perioral skin attachment and a silicone gel section positioned within the substrate for gentle lip contact. The design aims to balance secure mouth closure during sleep with trauma-free removal.

Cryolysis Adipose Tissue Sleep Apnea Treatment Patent Application

USPTO published patent application US20260096922A1 for methods, devices, and systems utilizing cryolysis of oropharyngeal adipose tissues to selectively remove fat cells causing obstructive sleep apnea. The application was filed December 10, 2025, by inventors Donald A. Gonzales and Anthony Natale, and published April 9, 2026. The invention employs a chilled liquid applied to target tissue at temperatures and durations sufficient to cause cryolysis.

Cell-Free Vascular Grafts and Graft Materials for Cellular Recruitment

USPTO published patent application US20260097149A1 for cell-free vascular graft materials incorporating bispecific binding partners with luminal and cellular binding domains for cellular recruitment. The application, filed June 26, 2023 under Application No. 18880781, covers fusion peptides with heparin and monocyte binding domains, methods of making the grafts, and methods of use including A-TEV technology.

Prosthetic Heart Valve Delivery Catheter With Safety Button

USPTO published patent application US20260096883A1 for a prosthetic heart valve delivery catheter assembly with a safety button mechanism. The invention includes a handle assembly with fixed main handle and rotating handles, an introducer sheath, and a distal tip assembly designed to limit trauma during valve deployment and catheter withdrawal. The application was filed on December 10, 2025, under application number 19415127.

Method for Treating Neurodegenerative Diseases with Polymer-Flavonoid Conjugates

The USPTO published patent application US20260097130A1 for a method of treating neurodegenerative diseases using polymer-flavonoid conjugates. Inventors Chun-Ting Cheng, Kuo-Liang Hou, and Pauline Ying Lau claim compositions that enable therapeutic materials to cross the blood-brain barrier. The application covers treatment of Alzheimer's disease, Parkinson's disease, Lewy body dementia, and Huntington's disease using the disclosed nanocomplex formulations.

Silver Nanoparticle Treatment for Carious Lesions, 3-5 Weeks

The USPTO published patent application US20260096959A1 filed by R.M CREIGHTON DENTAL PTY LTD for a method of treating carious lesions using silver nanoparticles. The treatment involves applying a first dental solution containing a silver salt followed by a second dental solution containing a reducing agent within less than 10 minutes. The lesion consolidates over 3-5 weeks to form a matte black crust containing nanoparticles. Invented by Graham G. Craig.

Anhydrous Powder Hair Lightening Suspension

USPTO published patent application US20260096960A1 by inventor David Erlingheuser for an anhydrous powder hair lightening suspension composition on April 9, 2026. The composition comprises 5-60% non-volatile oil, 3-30% petrolatum, 0.05-5% fumed silica, 1-70% persulfate salt, and 0% microplastics. This publication establishes a priority date and provides public notice of the pending patent claims.

Circular DNA Purification Using Nanoclays

USPTO published patent application US20260098252A1 by Texas State University (filed October 3, 2025) disclosing a method of purifying circular DNA from samples using nanoclays that preferentially adsorb contaminants including non-circular DNA, RNA, proteins, and endotoxins while leaving circular DNA unbound. The elution-free method separates nanoclay-contaminant complexes from the enriched circular DNA fraction. The invention also covers compositions and systems for such purification and methods of refining nanoclays for the purification process.

CO2 Conversion to C2+ Chemicals via Electrochemical and Microbial Process

USPTO published patent application US20260098282A1 disclosing a method for converting carbon dioxide to higher value C2+ chemicals using an electrochemical cell with a carbon dioxide reducing catalyst combined with microbial conversion. The application was filed on September 23, 2023, by inventors Peng Zhang, Kainan Chen, Joshua Shuhua Yuan, and Susie Y. Dai. The publication makes the application publicly available but does not constitute a granted patent.

Nucleic Acid Extraction Methods, Waters Corp, 9th Apr

Nucleic Acid Extraction Methods, Waters Corp, 9th Apr

Methods of Improving Unique Molecular Index Ligation Efficiency

Illumina, Inc. has filed a patent application (US20260098256A1) for methods and adapter pools that improve unique molecular index (UMI) ligation efficiency in nucleic acid sequencing applications. The invention enables more accurate quantification of polynucleotide fragments by providing UMIs that are uniquely associable with individual fragments. The application was published April 9, 2026, with a filing date of December 12, 2025. Biotechnology companies developing next-generation sequencing technologies may need to review this application to assess potential impacts on their IP strategies or freedom-to-operate analysis. Researchers and diagnostic developers using UMI-based sequencing methods should monitor this and related patent activity for potential licensing implications.

Lysis Vessel with Dual Membranes and Non-Magnetic Beads for On-Board Cell Lysis

USPTO published patent application US20260098253A1 assigned to Gen-Probe Incorporated. The application covers a lysis vessel for performing cell lysis that includes a laterally extending member and sleeve with dual porous membranes, non-magnetic beads, and at least one magnetic element contained within a lysis chamber. Filing date was December 11, 2025, under application number 19416385.

BEST1 Vectors for Retinal Dystrophy Treatment

The USPTO published patent application US20260098277A1 covering BEST1-targeted expression constructs, nucleic acid vectors, and pharmaceutical compositions for treating BEST1-associated retinal dystrophies including autosomal dominant bestrophinopathies. The application includes BEST1-targeted shRNAs, BEST1 coding sequences, promoters, and regulatory elements designed to improve functional BEST1 expression in subjects with BEST1 mutations. This published application represents an early-stage intellectual property filing with no granted rights or compliance obligations established.

In Vitro Bioproduction of Polyhydroxyalkanoate Monomers

USPTO published patent application US20260098283A1 by inventor Stephen Quirk for an enzymatic process to produce homogeneous chain length polyhydroxyalkanoate (PHA) monomers and polymers with chain lengths of at least eight carbons from long-chain fatty acids. The process enables specific, controlled production of PHA materials through in vitro enzyme contact with long-chain fatty acid precursors.

UORF Editing to Improve Crop Plant Agronomic Traits

USPTO published patent application US20260098275A1 assigned to Inari Agriculture Technology, Inc., disclosing methods of improving agronomic traits in crop plants through editing sequences within the 5' untranslated region (5' UTR) of plant genomes. The application names Ross Everett Altman, Malachy T. Campbell, Karl Anton Grothe Kremling, and Ruijuan Li as inventors. Filing date was April 10, 2024.

Protein Evolution System With DNA Synthesis, Microfluidics

The USPTO published patent application US20260098257A1 covering systems, methods, and kits for rapid protein evolution. The application (No. 19271120, filed July 16, 2025) names five inventors and describes a system combining DNA synthesis, microfluidic devices with sequestration pens, and a computing component for iterative protein optimization. The technology enables cell-free protein expression and assay-based evaluation of protein variants.

Root-Mediated Uptake of Guide RNA for Genomic Editing of a Plant

USPTO published patent application US20260098274A1 by Inari Agriculture Technology disclosing methods for editing plant genomes by delivering guide RNA to plant roots for CRISPR-Cas editing in meristems. Inventors include Aran McCay, Michael Lee Nuccio, and Palak Kathiria. The filing date was March 7, 2024.

DNA Origami Nanostructures for Molecular Data Storage Patent Application

USPTO published patent application US20260098258A1 on April 9, 2026, disclosing compositions and methods using DNA origami principles to package and archive data stored in multiple indexed DNA oligonucleotides. The application (No. 19319178, filed September 4, 2025) covers DNA origami (DNAO) nanostructures enabling selective physical data access and retrieval from a molecular pool.

KWS SAAT Immature Inflorescence Meristem Gene Editing

KWS SAAT SE & Co. KGaA has published a patent application (US20260098273A1) for a method of plant genome modification targeting immature inflorescence meristem (IIM) cells. The method uses genome editing systems with optional regeneration boosters, delivered via particle bombardment, to modify genomic target sites in plant cells and regenerate modified plant tissues, organs, or seeds.

Methods for Assaying Enriched Nucleic Acids Using Complementary Probes

The USPTO published patent application US20260098304A1 covering methods for assaying enriched nucleic acids using probes with sequences complementary to RNA expression products to determine expression levels of multiple genes. The application was filed on October 3, 2024 by inventors including Charles M. Perou, Joel S. Parker, and others. The claimed methods enable enrichment of nucleic acid molecules for gene expression analysis in biological samples.

Cell-Free PPi-Driven ATP Regeneration Platform Patent

Cell-Free PPi-Driven ATP Regeneration Platform Patent

CHIMERIC ANTIGEN RECEPTOR SPACERS

The USPTO published Lyell Immunopharma's patent application US20260098075A1 for chimeric antigen receptors (CARs) incorporating immunoglobulin-derived spacers, such as hinge or loop regions, designed to enhance cytokine release compared to CARs with non-Ig-derived spacers. The spacers may be derived from human immunoglobulins (IgAQ1, IgA2, IgD, IgE, IgG1-4, IgM) or non-human sources (e.g., mouse IgG2A), and may be configured as modular constructs combining multiple Ig hinges or fragments thereof. Filed September 8, 2025.

E-Vaping Device Formulation Level Indicator Patent Application

The USPTO published patent application US20260097173A1 for Altria Client Services LLC covering an electronic vaping device with a pre-vapor formulation level indicator. The device includes a vaporizer assembly with heating element, pre-vapor formulation reservoir, and discrete indicator segments controlled by a processor that determines duty cycle differences to adjust the indicator. The three inventors are Terrance Theodore Bache, Christopher S. Tucker, and Raymond W. Lau.

Multi Chamber Flexible Bag and Methods of Using Same

USPTO published patent application US20260096952A1 by inventor Antonio Francesco Di Naro for a multi-chamber flexible pharmaceutical bag designed to hold lyophilized products with a reconstituting solution. The bag features a frangible seal between chambers that breaks upon application of predetermined force to fluidly connect the chambers.

Aptar France Sas Spray Patent Analysis Method

USPTO published patent application US20260097411A1 assigned to Aptar France SAS, covering a method for analyzing spray generated by pharmaceutical fluid dispensing devices. The method uses strioscopy to display test fluid flow and determines spray compliance with specifications. Cycle time for analyzing one spray head is under 1.5 seconds.

Antibody Compositions with Antioxidants for Subcutaneous Delivery

The USPTO published patent application US20260097118A1 assigned to Bristol-Myers Squibb Company, covering pharmaceutical compositions comprising an antibody and at least two antioxidants formulated for subcutaneous delivery. The application includes claims for methods using an endoglycosidase hydrolase enzyme in the composition. Filing date was September 29, 2025.

Tissue Isolation Balloon Device for Radiotherapy

USPTO published patent application US20260097233A1, filed December 12, 2025, assigned to Beijing Qifan Bochuang Medical Technology Co., Ltd. The application covers a tissue isolation balloon device designed for repeated inflation and deflation in vivo during radiotherapy courses, with an isolation balloon positioned between healthy and target tissues to protect healthy tissue from radiation exposure.

Novel Formulations and Vehicles for DAPTZ Compounds Including Methylene Blue

USPTO published patent application US20260097043A1 assigned to WisTa Laboratories Ltd., covering novel oral pharmaceutical formulations of diaminophenothiazine (DAPTZ) compounds such as methylene blue. The application discloses gastro-retentive platforms including film-coated solid tablets and buoyant self-orientating capsules with sustained-release coatings. The filing was submitted on September 20, 2023, under application number 19113777.

Cholesterol Efflux Modulation Compositions and Methods - US20260097053A1

USPTO published patent application US20260097053A1 for compositions and methods modulating cholesterol efflux via ABCA1 for treating atherosclerosis and related diseases. Invented by Kailash Gulshan, the application claims PIP2 compositions affecting ABCA1 levels and promoting reverse cholesterol transport (RCT) to reduce cholesterol and atherosclerosis. This is a patent application publication establishing a filing date, not a granted patent.

Cancer Therapy Delivery System with Tumbling Container for Suspension Generation

USPTO published patent application US20260096951A1 for a cancer therapy delivery system featuring a tumbler vial for generating therapeutic microsphere suspensions. The system includes a rotation mechanism, fluid inlet and outlet lines configured to twist during rotation, and a cap occluding the vial end. The application was filed on October 9, 2025.

Urine Collection and Drainage Device and Methods of Use Thereof

The USPTO published patent application US20260096917A1 filed by LampLight Innovations, Inc. for an improved urine collection and drainage device. The application, filed October 7, 2025, was published April 9, 2026. The device comprises a vulva-facing portion with a bulbous protuberance, posterior ridge, and partial dome portion, along with a urine collection slot and a urine collection bag folded to create a one-way valve.

Ostomy Appliance Patent Application US20260096916A1

The USPTO published patent application US20260096916A1 for an ostomy appliance comprising a barrier with multiple layers (top layer with upper/lower piles, reinforcing layer, adherent layer with silicone gel) and an attached pouch. Inventors: Thomas R. Galbierz and Michael A. Galbierz. Application No. 19349631 filed October 3, 2025.

Solanum Lycopersicum Plants Having Improved Tobamovirus Resistance

The USPTO published patent application US20260096533A1 granting protection for hybrid Solanum lycopersicum tomato plants containing the Rug-1 resistance gene that confers Tomato Brown Rugose Fruit Virus (ToBRFV) tolerance/resistance. The patent covers the plant, seeds, fruits, plant parts, and methods for identifying, selecting, and producing ToBRFV-resistant tomato plants using the specified genetic marker.

Implantable Device for Administering a Therapeutic Agent

USPTO published patent application US20260096984A1 filed by inventors Harsh Patel and Jeffrey Haley on October 3, 2025. The application covers an implantable device for delivering therapeutic agents, featuring a core polymer matrix with hydrophobic poly ortho ester (POE) polymer having a glass transition temperature between -20°C and 40°C. The device is designed for controlled therapeutic agent release in vivo.

Understanding Responsibilities When Importing, Compounding and Supplying Unapproved Peptide Products

TGA has published a safety advisory warning of rising import, supply, compounding and advertising of unapproved peptide products in Australia. Products containing BPC-157, GHK-Cu, TB-500, retatrutide, and CJC-1295 are specifically identified as unapproved goods not evaluated for safety, quality, or effectiveness. The TGA states it is actively monitoring this issue from both safety and law enforcement perspectives and reminds affected parties of their obligations under the Therapeutic Goods Act 1989.