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FDA Proposed Collection of Information on Premarket Notifications

The FDA has proposed a new collection of information regarding premarket notifications. This is a request for comments on the proposed collection, with a deadline of May 18, 2026.

Priority review Consultation Healthcare
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FDA Draft Guidance on New Approach Methodologies in Drug Development

The FDA has issued draft guidance for industry on the use of New Approach Methodologies (NAMs) in drug development. This guidance provides recommendations for sponsors on how to incorporate NAMs into their regulatory submissions. The comment period for this draft guidance closes on May 18, 2026.

Priority review Guidance Pharmaceuticals
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Civil Rights Cold Case Records Review Board - Records Release Notice

The Civil Rights Cold Case Records Review Board has issued a notice regarding a formal determination on records release. This notice, published in the Federal Register, outlines the board's decision concerning the accessibility of specific records.

Routine Notice Public Health
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AbilityOne Commission Procurement List Deletions

The AbilityOne Commission has announced deletions from its Procurement List. These changes affect items that are no longer required or available through the AbilityOne program. The effective date for these deletions is April 19, 2026.

Routine Notice Government Contracting
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Procurement List Proposed Additions and Deletions

The Committee for Purchase From People Who Are Blind or Severely Disabled has published proposed additions and deletions to its procurement list. This notice includes a 30-day comment period for interested parties.

Priority review Consultation Government Contracting
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Committee for Purchase From People Who Are Blind or Severely Disabled Public Meeting Notice

The Committee for Purchase From People Who Are Blind or Severely Disabled has announced an upcoming public meeting. The meeting is scheduled for April 22, 2026, and will cover topics related to the Committee's operations. This notice serves to inform interested parties of the meeting details.

Routine Notice Employment & Labor
Missouri AG - News
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Missouri AG Leads 15 States Supporting Uniform Herbicide Labeling

Missouri Attorney General Catherine Hanaway led a 15-state coalition in filing an amicus brief with the U.S. Supreme Court supporting uniform labeling requirements for herbicides like glyphosate. The brief argues against state-specific mandates that could disrupt supply chains and harm farmers.

Priority review Enforcement Environmental Protection
Missouri AG - News
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Missouri AG Defends Redistricting Map Against Challenge

Missouri Attorney General Catherine Hanaway announced a victory in Jackson County, where the court upheld the Missouri FIRST Map against a constitutional challenge. The ruling rejected claims that the map violated compactness and equal population requirements, affirming the General Assembly's authority in redistricting.

Priority review Enforcement Judicial Administration
Missouri AG - News
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Missouri AG Leads 21 States Supporting Election Integrity Laws at SCOTUS

Missouri Attorney General Catherine Hanaway led a coalition of 21 states in an amicus brief to the U.S. Supreme Court. The brief supports overturning a federal appellate court ruling that struck down a Pennsylvania law requiring voters to date mail-in ballots, arguing it upholds election integrity.

Priority review Enforcement Judicial Administration
Missouri AG - News
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Missouri AG Files Felony Charges for Illegal Gaming Devices

Missouri Attorney General Catherine Hanaway announced felony charges against a Greene County business owner for operating 12 illegal slot machines. The Attorney General's Office also filed a civil action seeking an injunction against the business, Briarwood One Stop, and its managing officer, Himanshu Patel.

Urgent Enforcement Consumer Protection
Missouri AG - News
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Missouri AG Secures Civil Commitment of Sexually Violent Predator

Missouri Attorney General Catherine Hanaway announced the civil commitment of Dwaine Paige, a sexually violent predator, following a jury trial. Paige will be committed to the Department of Mental Health for control, care, and treatment due to his history of violent and sexual offenses and a diagnosed mental abnormality.

Priority review Enforcement Criminal Justice
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FDA Guidance on Pyrogen and Endotoxin Testing

The FDA has issued guidance for biological product, drug, and device firms regarding pyrogen and endotoxin testing. This document provides recommendations based on current FDA thinking concerning USP and AAMI standards for bacterial endotoxin and pyrogen tests.

Routine Guidance Healthcare
UK CMA Publications
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Subsidy Advice Unit reviews Clean Industry Bonus Scheme

The UK's Subsidy Advice Unit (SAU) has accepted a request to review the Department for Energy Security and Net Zero's proposed Clean Industry Bonus Allocation Round 8 Scheme. The SAU will provide advice on whether the scheme complies with subsidy control requirements, with a report due by April 30, 2026.

Priority review Consultation Energy
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BNSF TGMS Waiver Initial Notification Public Comment

The Federal Railroad Administration (FRA) is accepting public comments on an initial notification for a waiver request submitted by BNSF regarding their Track Geometry Measurement System (TGMS). This is an opportunity for interested parties to provide input on the waiver application.

Routine Consultation Transportation
FDA Warning Letters
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FDA Warning Letter to Vedic Lifesciences for GLP Violations

The FDA issued a warning letter to Vedic Lifesciences Pvt. Ltd. for violations of Good Laboratory Practice (GLP) regulations during the inspection of nonclinical laboratory studies. The company failed to prepare accurate final reports for investigational drug studies, misrepresenting testing facility and personnel information.

Urgent Enforcement Healthcare
Pennsylvania DOH News
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Pennsylvania Delivers $6.6 Million for EMS Professionals

The Pennsylvania administration announced the delivery of $6.6 million to equip Emergency Medical Services (EMS) professionals across the Commonwealth. This funding, part of the 2025-26 budget, aims to recruit, train, and equip EMS personnel to improve response times and save lives.

Routine Notice Healthcare
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NHTSA Agency Information Collection Activities; Comment Request

The National Highway Traffic Safety Administration (NHTSA) has issued a notice requesting public comment on its agency information collection activities, specifically concerning the Crash Report Sampling System (CRSS), Non-Traffic Surveillance (NTS), and Special Study Data Collection. The comment period is open for 60 days.

Priority review Notice Transportation
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FRA Interim Order on Emergency Qualifications

The Federal Railroad Administration (FRA) has issued an interim order concerning emergency qualifications for railroad employees. This order introduces new requirements and procedures related to employee qualifications in emergency situations.

Priority review Rule Transportation
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FRA Waiver Letter - Billerud

The Federal Railroad Administration (FRA) has received a waiver letter submission from Billerud. This document is a notification of the submission and does not contain the waiver details themselves.

Routine Notice Transportation
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FRA Acknowledgment Letter

The Federal Railroad Administration (FRA) has issued an acknowledgment letter related to docket FRA-2025-0985. This notice confirms the receipt of a submission and provides a reference for the correspondence.

Routine Notice Transportation
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FRA Acknowledgment Letter for Docket FRA-2025-0984

The Federal Railroad Administration (FRA) has posted an acknowledgment letter related to Docket FRA-2025-0984. This notice confirms the receipt of a submission for the specified docket.

Routine Notice Transportation
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Federal Railroad Administration OCRB Decision

The Federal Railroad Administration (FRA) has posted an OCRB Decision related to docket FRA-2024-0117-0006. The document is available for download as an attachment.

Routine Notice Transportation
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FRA Acknowledgment Letter for Docket FRA-2025-0951

The Federal Railroad Administration (FRA) has posted an acknowledgment letter related to Docket FRA-2025-0951. This notice confirms the receipt of a submission for the specified docket.

Routine Notice Transportation
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FRA Interim Order on Equipment Qualification and Approval

The Federal Railroad Administration (FRA) has issued an interim order regarding equipment qualification and approval processes. This order, identified by docket number FRA-2025-1021-0003, establishes new procedural requirements for equipment.

Priority review Rule Transportation
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FRA OCRB Decision

The Federal Railroad Administration (FRA) has issued a decision from its Office of Compliance and Records Bureau (OCRB). The document is available for download via regulations.gov.

Routine Notice Transportation
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FRA Waiver Extension Petition Docket FRA-2020-0030

The Federal Railroad Administration (FRA) has posted an updated waiver extension petition for docket FRA-2020-0030. The document, titled 'FRA waiver extension petition docket FRA-2020-0030 posted Mar 18', is available as an attachment.

Routine Notice Transportation
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FRA Docket Acknowledgment Letter

The Federal Railroad Administration (FRA) has posted an acknowledgment letter for docket FRA-2025-1021. This notice confirms the receipt and processing of a submission related to the specified docket.

Routine Notice Transportation
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FRA - BNSF TGMS Waiver Notification

The Federal Railroad Administration (FRA) has posted a waiver notification regarding BNSF's TGMS system. The notice was posted on March 6, 2026, and is available for review via the provided URL.

Routine Notice Transportation
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FRA Request for Hearing

The Federal Railroad Administration (FRA) has received a request for a hearing related to docket FRA-2024-0106-0006. The specific details of the case or the parties involved are not provided in the available information.

Routine Enforcement Transportation
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OCRB Interim Order posted Mar 18, 2026 by FRA

OCRB Interim Order posted Mar 18, 2026 by FRA

Routine Notice
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FRA OCRB Decision

The Federal Railroad Administration (FRA) has posted a decision from its Office of Railroad Compliance and Assurance (ORCB) related to docket FRA-2024-0073. The decision is dated March 18, 2026.

Routine Enforcement Transportation
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FRA Interim Order on OCRB

The Federal Railroad Administration (FRA) has issued an interim order concerning the Office of Civil Rights and Compliance (OCRB). This order, dated March 18, 2026, is associated with Docket FRA-2025-0984. Further details on the specific requirements and implications are pending the availability of the document content.

Priority review Rule Transportation
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FRA OCRB Decision

The Federal Railroad Administration (FRA) has posted an OCRB Decision related to docket FRA-2024-0114. This document is now closed for comments, indicating a potential shift towards finalization or further action.

Priority review Consultation Transportation
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Rural Housing Service Amends Single Family Housing Guaranteed Loan Program

The Rural Housing Service has published a final rule amending regulations for the Single Family Housing Guaranteed Loan Program. These changes are effective June 17, 2026, with implementation on September 28, 2028.

Priority review Rule Housing
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Rural Housing Service 502 Loan Program LITE Pilot Program

The Rural Housing Service (RHS) has issued a notice announcing the Single Family Housing Section 502 Guaranteed Loan Program Lender Interactive Test Environment (LITE) Delegated Authority Pilot Program. This pilot program aims to test a new delegated authority process for lenders participating in the 502 loan program.

Routine Notice Housing
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CFTC Withdraws Climate-Related Financial Risk Information Request

The Commodity Futures Trading Commission (CFTC) has withdrawn its June 8, 2022, Request for Information (RFI) on climate-related financial risk. This withdrawal is effective March 16, 2026, and is attributed to the revocation of Executive Order 14030 and the existence of existing regulatory frameworks.

Routine Notice Financial Services
CO Securities Sitemap
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Colorado Securities Division Launches New IAR CE Course Catalog

The Colorado Division of Securities has announced a new online public course catalog for investment adviser representatives (IARs) to find approved continuing education (CE) courses. This catalog, launched by NASAA, centralizes course offerings and allows filtering by various criteria to help IARs meet their annual CE requirements.

Routine Notice Securities
ISDA News
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David Bailey discusses Basel 3.1 framework and regulatory consistency

The Bank of England's Prudential Regulation Authority has finalized its Basel 3.1 framework, set for implementation at the start of 2027. An interview with David Bailey discusses the framework's implications, emphasizing global consistency and balancing regulation in evolving markets.

Priority review Notice Banking
ISDA News
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ISDA Responds to Bank of England on Derivatives Clearing Exemption

ISDA has submitted a response to the Bank of England's consultation regarding an exemption for post-trade risk reduction (PTRR) transactions from the derivatives clearing obligation under EMIR. ISDA supports the proposed principles-based approach and suggests immediate availability of the exemption upon finalization.

Priority review Consultation Financial Services
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Library of Congress Photography Rules Updated

The Library of Congress has updated its rules regarding photography on its premises, instituting a new permit process. These changes are effective March 19, 2026.

Routine Rule Government Contracting
FR: Forest Service
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Forest Service Seeks Comments on Grazing Permit Forms Renewal

The Forest Service is seeking public comments on the renewal of information collection requirements related to grazing permit administration forms. The comment period is open for 60 days, closing on May 18, 2026.

Routine Consultation Agriculture
FR: Forest Service
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Forest Service National Urban and Community Forestry Advisory Council Meeting Notice

The Forest Service has issued a notice announcing a public meeting of the National Urban and Community Forestry Advisory Council. The virtual meeting is scheduled for April 10, 2026, and will cover topics related to urban and community forestry initiatives.

Routine Notice Environmental Protection
FR: Forest Service
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Forest Service Special Uses Regulations Updated for Filming

The Forest Service has updated its special uses regulations concerning filming and photography. These changes are effective March 19, 2026, and aim to streamline processes for commercial filming permits on National Forest System lands.

Routine Rule Environmental Protection
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WTC Health Program Denies Petition for Anti-GBM Glomerulonephritis

The Centers for Disease Control and Prevention (CDC) has issued a notice denying Petition 026 for the addition of Anti-Glomerular Basement Membrane (Anti-GBM) Glomerulonephritis to the World Trade Center (WTC) Health Program. The agency found insufficient evidence to support its inclusion.

Routine Notice Healthcare
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FCC Notice of Violation to Armada Media

The FCC issued a Notice of Violation to Armada Media for unauthorized operation of radio stations K291BW and WQJS618. This action stems from violations noted in the Enforcement Bureau's report.

Priority review Enforcement Telecommunications
IAPP Privacy News
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AI Standards, Regulations, and Enforcement Efforts Discussed

Global jurisdictions are discussing policies for responsible AI development and use, but the pace of AI innovation is outpacing regulation. Stakeholders at the AI Standards Hub Global Summit 2026 highlighted the importance of technical standards and assurance systems in guiding compliance amidst evolving regulatory frameworks like the EU AI Act and a patchwork of US state laws.

Priority review Notice Artificial Intelligence
IAPP Privacy News
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GDPR Article 25: Data Protection by Design and Default Factors

This analysis discusses the implementation of GDPR Article 25, focusing on data protection by design and by default. It highlights the importance of continuously assessing state of the art, cost of implementation, processing context, and risks to individuals, especially with the rise of AI.

Priority review Guidance Data Privacy
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CISA KEV: Zimbra Collaboration XSS Vulnerability CVE-2025-66376

CISA has added a known exploited vulnerability, CVE-2025-66376, affecting Zimbra Collaboration. This cross-site scripting (XSS) vulnerability requires immediate attention from federal agencies and organizations using the affected software.

Urgent Notice Cybersecurity
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CISA KEV: Microsoft SharePoint RCE Vulnerability (CVE-2026-20963)

CISA has added a Microsoft SharePoint remote code execution vulnerability (CVE-2026-20963) to its Known Exploited Vulnerabilities (KEV) catalog. The vulnerability has a CVSS score of 8.8 and is actively exploited.

Urgent Notice Cybersecurity
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IRS Seeks Comments on Qualified Revocable Trust Tax Election Burden

The IRS has published a notice inviting public comments on the burden associated with the election to treat a qualified revocable trust as part of an estate for tax purposes. The comment period is open for 60 days.

Priority review Consultation Taxation

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