VAP-Measured Lipid Subfractions and In-Stent Restenosis After PCI (NCT07533656)

NIH ClinicalTrials.gov registered a new observational study (NCT07533656) examining whether vertical auto profile (VAP)-measured lipid and lipoprotein subfractions are associated with coronary in-stent restenosis following percutaneous coronary intervention. The study has two components: a retrospective cross-sectional arm enrolling patients with prior PCI undergoing repeat coronary angiography, and a prospective follow-up arm enrolling patients undergoing index PCI. Serum samples from routine clinical blood draws will be used for VAP testing without additional phlebotomy.

This study registration represents administrative documentation of a planned clinical investigation and does not create compliance obligations for regulated entities. Healthcare providers and clinical investigators conducting cardiovascular research may reference this registry for protocol considerations. The study's findings, upon completion, may inform clinical understanding of lipid subfraction associations with restenosis but will not itself impose regulatory requirements.