Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients

NIH registered a new clinical trial on ClinicalTrials.gov for a randomized controlled study evaluating the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients. Eighty participants will be enrolled in two parallel groups receiving either scaling and root planing with adjunctive diode laser therapy or scaling and root planing alone. The trial will evaluate clinical periodontal parameters, blood biomarkers, radiographic findings, and subgingival microbiome profiles through April 2026.

Healthcare providers and clinical investigators conducting periodontal or transplant research may encounter related protocols or patient inquiries about adjunctive laser therapies. The trial represents standard post-market clinical evaluation rather than a regulatory action. Compliance officers should note this as informational research activity rather than a compliance-relevant document.