Potassium Channel Study in Chronic Cocaine Users
ClinicalTrials.gov Studies
Summary
NIH registered a clinical trial (NCT07532460) on ClinicalTrials.gov investigating the role of potassium channels in working memory impairments among chronic cocaine users. The study will test 4-aminopyridine (4-AP) versus placebo as an intervention for cognitive impairments associated with cocaine use disorder. The trial is registered with an estimated start date of April 16, 2026.
What changed
NIH registered a new clinical trial on ClinicalTrials.gov to investigate the neurobiological basis of cognitive impairments in chronic cocaine users. The study will examine whether acute potassium channel blockade via 4-aminopyridine affects working memory and other cognitive functions compared to placebo.
Healthcare providers and clinical investigators conducting substance use disorder research may need to be aware of this trial for potential collaboration or to avoid duplicative studies. Patients with cocaine use disorder experiencing cognitive impairments may benefit from understanding ongoing research in this area.
What to do next
- Monitor for updates
Archived snapshot
Apr 16, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine Users
N/A NCT07532460 Kind: NA Apr 16, 2026
Abstract
The study aims to address the neurobiological basis of cognitive impairments in chronic cocaine users by investigating the potential impact of an acute potassium channel blockade on working memory performance and other cognitive functions.
Conditions: Cognitive Impairments in Cocaine Use Disorder
Interventions: 4-aminopyridine (4-AP), Placebo
Related changes
Get daily alerts for ClinicalTrials.gov Studies
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from NIH.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when ClinicalTrials.gov Studies publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.