Efficacy of Multi-Type Photolithography Flat Microstructure Lenses for Childhood Myopia Control
Summary
NIH ClinicalTrials.gov registered a clinical trial (NCT07535658) studying photolithography flat microstructure lenses for childhood myopia prevention and control. The randomized controlled trial will compare plano microstructure lenses with multi-point defocus design against Spectacle Lenses with Aspherical Lenslets (Essilor Stellest) in children over a 1-year period.
What changed
NIH registered a new clinical trial (NCT07535658) on ClinicalTrials.gov studying the efficacy and safety of multi-type photolithography flat microstructure lenses for childhood myopia control. The trial includes five study arms testing lenses with varying optical properties including multi-point defocus design, photochromic properties at different light transmittance levels (55% and 35% post-activation), and contrast sensitivity reduction.
For manufacturers of pediatric ophthalmic devices, this trial represents emerging competition in the myopia control lens market. The study compares photolithography plano microstructure lenses against commercially available Spectacle Lenses with Aspherical Lenslets (Essilor Stellest), potentially establishing comparative efficacy data that could influence future regulatory submissions and market positioning for myopia control devices.
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Apr 18, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Efficacy of Multi-Type Photolithography Flat Microstructure Lenses for Childhood Myopia Control
N/A NCT07535658 Kind: NA Apr 17, 2026
Abstract
The goal of this clinical trial is to learn if photolithographic flat microstructure lenses work to prevent myopia in children. It will also learn about the safety of different designs of photolithographic flat microstructure lenses. The main questions it aims to answer are:
Are photolithography flat microstructure lenses effective and safe in preventing myopia in children? Does the depth of tinted lenses affect visual quality? Researchers will compare photolithography flat microstructure lenses to a spectacle lenses with aspherical lenslets to see if photolithography flat microstructure lenses works to prevent myopia in children.
Participants will:
Wear photolithography flat microstructure lenses or Spectacle Lenses with Aspherical Lenslets more than 8H per day for 1 year.
Visit the clinic once every 3 months for checkups and tests.
Conditions: Myopia
Interventions: wearing photolithography plano microstructure lenses with multi-point defocus design, non-fading optical property, wearing Plano microstructure lenses featuring multi-point defocus design with aspherical lenslets (Essilor Stellest), wearing Photolithography Plano Microstructure Lenses incorporates a multi-point defocus optical architecture , featuring photochromic properties with a light transmittance of 55% post-activation, wearing Photolithography Plano Microstructure Lenses incorporates a multi-point defocus optical architecture , featuring photochromic properties with a light transmittance of 35% post-activation, wearing Photolithography Plano Microstructure Lenses designed to reduce contrast sensitivity and featuring a non-fading optical property
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