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OMT vs Exercise in TMD Clinical Trial

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Summary

NIH ClinicalTrials.gov registered a randomized clinical trial (NCT07534540) comparing osteopathic manipulative treatment (OMT) versus a structured home-based exercise program in adults diagnosed with myogenic temporomandibular disorders (TMD). The trial will assess pain intensity, functional outcomes, postural stability, and quality of life across intervention groups. Enrollment status and specific trial sites are not detailed in the registry record.

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What changed

A clinical trial registration was entered into the NIH ClinicalTrials.gov registry documenting a randomized controlled study comparing OMT and home-based exercise interventions for adults with myogenic TMD. Participants will be randomly assigned to receive either OMT or the exercise program, with assessments measuring pain intensity, pressure pain thresholds, mandibular movements, cervical range of motion, postural stability, and quality of life at baseline and follow-up.

The registry record provides prospective research participants and clinical investigators informational details about an ongoing comparative effectiveness study. Healthcare providers treating TMD patients may reference this trial for emerging evidence on OMT versus structured exercise approaches. The record does not create compliance obligations but serves as an administrative registration of an approved clinical investigation.

Archived snapshot

Apr 17, 2026

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← ClinicalTrials.gov Studies

OMT vs Exercise in TMD

N/A NCT07534540 Kind: NA Apr 16, 2026

Abstract

The goal of this clinical trial is to evaluate whether different rehabilitation approaches can improve pain, function, and postural control in individuals with temporomandibular disorders (TMD). The study focuses on adults diagnosed with myogenic TMD.

The main questions it aims to answer are:

Does osteopathic manipulative treatment (OMT) reduce pain and improve functional outcomes in individuals with TMD? Does a structured home-based exercise program improve postural control and sensorimotor function in individuals with TMD? Researchers will compare osteopathic manipulative treatment (OMT) and a home-based exercise program to determine their relative effects on pain, function, and postural stability.

Participants will:

Be randomly assigned to either the OMT group or the exercise group Receive the assigned intervention over the study period Undergo assessments before and after treatment, including pain intensity, pressure pain threshold, mandibular movements, cervical range of motion, postural stability, and quality of life

Conditions: Temporomandibular Disorder (TMD), Osteoapthic Manipulation Treatment

Interventions: Home-based Exercise Program, Osteopathic Manipulative Treatment (OMT)

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Last updated

Classification

Agency
NIH
Published
April 16th, 2024
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07534540

Who this affects

Applies to
Clinical investigators Healthcare providers
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Rehabilitation therapy research Pain management study
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Pharmaceuticals Medical Devices

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